FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040754927> ?p ?o ?g. }

• W2040754927 endingPage "251" @default.
• W2040754927 startingPage "239" @default.
• W2040754927 abstract "Our purpose was to investigate the presence of nuclear specific elements of the phosphoinositide pathway, and the link between nuclear calcium events and the first step of meiosis resumption, i.e. germinal vesicle breakdown (GVB) in mouse immature oocytes. Using confocal laser scanning microscopy, we analyzed the effects of nuclear microinjection of inositol 1,4,5-trisphosphate (InsP3), heparin and anti-InsP3 receptor monoclonal antibodies on both spontaneous nuclear and cytoplasmic calcium oscillations, as well as the effects of these components on the GVB. First we observed that nuclear Ca2+ events were dependent upon both nucleoplasmic and cytoplasmic InsP3 levels, highlighting a cross-talk between the GV and the cytoplasm concerning the Ca2+/InsP3 pathway. We demonstrated also that: 1) type 1 InsP3 receptors were localized at the nuclear membrane level while type 3 were absent from the nucleus; 2) calcium release from nuclear stores was mediated by type 1 rather than type 3 InsP3 receptor associated channels; 3) the anti-InsP3 R-1 mAB microinjected into the nucleus inhibited the GVB. These results demonstrate that reinitiation of meiosis requires an increase in nuclear phosphoinositide dependent Ca2+. Thus, the role of nuclear Ca2+ homeostasis is discussed with particular emphasis on nuclear envelope dynamics." @default.
• W2040754927 created "2016-06-24" @default.
• W2040754927 creator A5008144388 @default.
• W2040754927 creator A5018711684 @default.
• W2040754927 creator A5051143864 @default.
• W2040754927 date "1998-10-01" @default.
• W2040754927 modified "2023-10-17" @default.
• W2040754927 title "Nuclear calcium release by InsP3-receptor channels plays a role in meiosis reinitiation in the mouse oocyte" @default.
• W2040754927 cites W1496221368 @default.
• W2040754927 cites W1517921781 @default.
• W2040754927 cites W1589002191 @default.
• W2040754927 cites W1603199903 @default.
• W2040754927 cites W1666469474 @default.
• W2040754927 cites W1834569838 @default.
• W2040754927 cites W1963611129 @default.
• W2040754927 cites W1966150568 @default.
• W2040754927 cites W1968709828 @default.
• W2040754927 cites W1971119290 @default.
• W2040754927 cites W1976993112 @default.
• W2040754927 cites W1981105310 @default.
• W2040754927 cites W1981245243 @default.
• W2040754927 cites W1984482377 @default.
• W2040754927 cites W1984885629 @default.
• W2040754927 cites W1994805322 @default.
• W2040754927 cites W1995554863 @default.
• W2040754927 cites W2001141372 @default.
• W2040754927 cites W2002971054 @default.
• W2040754927 cites W2003247910 @default.
• W2040754927 cites W2003465766 @default.
• W2040754927 cites W2020687188 @default.
• W2040754927 cites W2025914465 @default.
• W2040754927 cites W2026770951 @default.
• W2040754927 cites W2036664585 @default.
• W2040754927 cites W2037735671 @default.
• W2040754927 cites W2042128989 @default.
• W2040754927 cites W2046395732 @default.
• W2040754927 cites W2049121094 @default.
• W2040754927 cites W2050990782 @default.
• W2040754927 cites W2060794679 @default.
• W2040754927 cites W2071328955 @default.
• W2040754927 cites W2071556519 @default.
• W2040754927 cites W2072732151 @default.
• W2040754927 cites W2086892519 @default.
• W2040754927 cites W2089021149 @default.
• W2040754927 cites W2099430463 @default.
• W2040754927 cites W2110499044 @default.
• W2040754927 cites W2117217469 @default.
• W2040754927 cites W2322670664 @default.
• W2040754927 cites W2397904797 @default.
• W2040754927 doi "https://doi.org/10.1016/s0143-4160(98)90048-3" @default.
• W2040754927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9883278" @default.
• W2040754927 hasPublicationYear "1998" @default.
• W2040754927 type Work @default.
• W2040754927 sameAs 2040754927 @default.
• W2040754927 citedByCount "42" @default.
• W2040754927 countsByYear W20407549272012 @default.
• W2040754927 countsByYear W20407549272014 @default.
• W2040754927 countsByYear W20407549272015 @default.
• W2040754927 countsByYear W20407549272016 @default.
• W2040754927 countsByYear W20407549272017 @default.
• W2040754927 countsByYear W20407549272019 @default.
• W2040754927 countsByYear W20407549272022 @default.
• W2040754927 crossrefType "journal-article" @default.
• W2040754927 hasAuthorship W2040754927A5008144388 @default.
• W2040754927 hasAuthorship W2040754927A5018711684 @default.
• W2040754927 hasAuthorship W2040754927A5051143864 @default.
• W2040754927 hasConcept C126725582 @default.
• W2040754927 hasConcept C152624196 @default.
• W2040754927 hasConcept C170493617 @default.
• W2040754927 hasConcept C190062978 @default.
• W2040754927 hasConcept C196843134 @default.
• W2040754927 hasConcept C2776690073 @default.
• W2040754927 hasConcept C2777427919 @default.
• W2040754927 hasConcept C2780114586 @default.
• W2040754927 hasConcept C2780723820 @default.
• W2040754927 hasConcept C2994119143 @default.
• W2040754927 hasConcept C55493867 @default.
• W2040754927 hasConcept C59157529 @default.
• W2040754927 hasConcept C62525196 @default.
• W2040754927 hasConcept C86803240 @default.
• W2040754927 hasConcept C95444343 @default.
• W2040754927 hasConceptScore W2040754927C126725582 @default.
• W2040754927 hasConceptScore W2040754927C152624196 @default.
• W2040754927 hasConceptScore W2040754927C170493617 @default.
• W2040754927 hasConceptScore W2040754927C190062978 @default.
• W2040754927 hasConceptScore W2040754927C196843134 @default.
• W2040754927 hasConceptScore W2040754927C2776690073 @default.
• W2040754927 hasConceptScore W2040754927C2777427919 @default.
• W2040754927 hasConceptScore W2040754927C2780114586 @default.
• W2040754927 hasConceptScore W2040754927C2780723820 @default.
• W2040754927 hasConceptScore W2040754927C2994119143 @default.
• W2040754927 hasConceptScore W2040754927C55493867 @default.
• W2040754927 hasConceptScore W2040754927C59157529 @default.
• W2040754927 hasConceptScore W2040754927C62525196 @default.
• W2040754927 hasConceptScore W2040754927C86803240 @default.
• W2040754927 hasConceptScore W2040754927C95444343 @default.
• W2040754927 hasIssue "4" @default.
• W2040754927 hasLocation W20407549271 @default.

• next