Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040759543> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2040759543 endingPage "1128" @default.
- W2040759543 startingPage "1121" @default.
- W2040759543 abstract "The purpose of the meta-analysis was to understand the antitussive effect of treatment with dextromethorphan hydrobromide, 30 mg, vs placebo over a 3-h treatment period in patients with cough due to uncomplicated upper respiratory tract infection (URTI), and to show that the computerized system for acquisition and analysis of cough sound was consistent and reproducible across the individual studies.The six studies used for the meta-analysis were randomized, double-blind, parallel-group, single-dose, placebo-controlled studies with a 3-h postdose cough evaluation period.One study was conducted in Durban, South Africa, and five studies were conducted in Bombay, India. Four studies took place in clinics, and two studies were in-home studies.Seven hundred ten adult patients with cough due to uncomplicated URTI who were otherwise healthy and who satisfied the inclusion/exclusion criteria for the meta-analysis.For each patient, a standard baseline was calculated pretreatment, then a 3-h continuous cough recording was made after treatment was initiated. Five efficacy variables were measured in 30-min intervals: cough bouts, cough components, cough effort, cough intensity, and cough latency. The meta-analysis showed consistent results across most of the studies for each of the efficacy variables. It demonstrated significantly greater overall reductions in cough bouts, cough components, and cough effort, and an increase in cough latency for patients treated with dextromethorphan hydrobromide, 30 mg, vs those treated with placebo.The results of a meta-analysis of the six clinical studies show that the antitussive effect of a single dose of dextromethorphan hydrobromide, 30 mg, has been established. The consistent nature of the results shows that the computerized cough acquisition and analysis system is a valid and reproducible methodology for evaluating cough associated with URTI." @default.
- W2040759543 created "2016-06-24" @default.
- W2040759543 creator A5015582808 @default.
- W2040759543 creator A5044014451 @default.
- W2040759543 creator A5067514047 @default.
- W2040759543 date "2001-10-01" @default.
- W2040759543 modified "2023-10-13" @default.
- W2040759543 title "Application and Validation of a Computerized Cough Acquisition System for Objective Monitoring of Acute Cough" @default.
- W2040759543 cites W1966785714 @default.
- W2040759543 cites W1969502111 @default.
- W2040759543 cites W1988500732 @default.
- W2040759543 cites W1989767619 @default.
- W2040759543 cites W1994705765 @default.
- W2040759543 cites W1997842031 @default.
- W2040759543 cites W2023490408 @default.
- W2040759543 cites W2037353966 @default.
- W2040759543 cites W2051817539 @default.
- W2040759543 cites W2067928297 @default.
- W2040759543 cites W2089297649 @default.
- W2040759543 cites W2098184132 @default.
- W2040759543 cites W2116446898 @default.
- W2040759543 cites W2403118915 @default.
- W2040759543 doi "https://doi.org/10.1378/chest.120.4.1121" @default.
- W2040759543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11591548" @default.
- W2040759543 hasPublicationYear "2001" @default.
- W2040759543 type Work @default.
- W2040759543 sameAs 2040759543 @default.
- W2040759543 citedByCount "118" @default.
- W2040759543 countsByYear W20407595432012 @default.
- W2040759543 countsByYear W20407595432013 @default.
- W2040759543 countsByYear W20407595432014 @default.
- W2040759543 countsByYear W20407595432015 @default.
- W2040759543 countsByYear W20407595432016 @default.
- W2040759543 countsByYear W20407595432017 @default.
- W2040759543 countsByYear W20407595432018 @default.
- W2040759543 countsByYear W20407595432019 @default.
- W2040759543 countsByYear W20407595432020 @default.
- W2040759543 countsByYear W20407595432021 @default.
- W2040759543 countsByYear W20407595432022 @default.
- W2040759543 countsByYear W20407595432023 @default.
- W2040759543 crossrefType "journal-article" @default.
- W2040759543 hasAuthorship W2040759543A5015582808 @default.
- W2040759543 hasAuthorship W2040759543A5044014451 @default.
- W2040759543 hasAuthorship W2040759543A5067514047 @default.
- W2040759543 hasConcept C126322002 @default.
- W2040759543 hasConcept C142724271 @default.
- W2040759543 hasConcept C204787440 @default.
- W2040759543 hasConcept C27081682 @default.
- W2040759543 hasConcept C2776012195 @default.
- W2040759543 hasConcept C2780805593 @default.
- W2040759543 hasConcept C2781245242 @default.
- W2040759543 hasConcept C42219234 @default.
- W2040759543 hasConcept C534529494 @default.
- W2040759543 hasConcept C71924100 @default.
- W2040759543 hasConcept C95190672 @default.
- W2040759543 hasConceptScore W2040759543C126322002 @default.
- W2040759543 hasConceptScore W2040759543C142724271 @default.
- W2040759543 hasConceptScore W2040759543C204787440 @default.
- W2040759543 hasConceptScore W2040759543C27081682 @default.
- W2040759543 hasConceptScore W2040759543C2776012195 @default.
- W2040759543 hasConceptScore W2040759543C2780805593 @default.
- W2040759543 hasConceptScore W2040759543C2781245242 @default.
- W2040759543 hasConceptScore W2040759543C42219234 @default.
- W2040759543 hasConceptScore W2040759543C534529494 @default.
- W2040759543 hasConceptScore W2040759543C71924100 @default.
- W2040759543 hasConceptScore W2040759543C95190672 @default.
- W2040759543 hasIssue "4" @default.
- W2040759543 hasLocation W20407595431 @default.
- W2040759543 hasLocation W20407595432 @default.
- W2040759543 hasOpenAccess W2040759543 @default.
- W2040759543 hasPrimaryLocation W20407595431 @default.
- W2040759543 hasRelatedWork W1999126011 @default.
- W2040759543 hasRelatedWork W2010215880 @default.
- W2040759543 hasRelatedWork W2047454295 @default.
- W2040759543 hasRelatedWork W2050941802 @default.
- W2040759543 hasRelatedWork W2074961489 @default.
- W2040759543 hasRelatedWork W2206563184 @default.
- W2040759543 hasRelatedWork W2376472092 @default.
- W2040759543 hasRelatedWork W2794487796 @default.
- W2040759543 hasRelatedWork W3030512125 @default.
- W2040759543 hasRelatedWork W3127400364 @default.
- W2040759543 hasVolume "120" @default.
- W2040759543 isParatext "false" @default.
- W2040759543 isRetracted "false" @default.
- W2040759543 magId "2040759543" @default.
- W2040759543 workType "article" @default.