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- W2040759600 abstract "The number of studies with segments of renal tubules from nonmammalian vertebrates isolated and perfused in vitro has increased substantially in recent years. These studies involve renal tubules from fish, amphibians, and reptiles. The motives for such studies range from a desire to understand the renal adaptations of nonmammalian vertebrates to their environment to a need to find a preparation appropriate for a particular area of study. Tubules from a number of nonmammalian vertebrates, despite difficulties in isolation and perfusion, offer special advantages for some studies. Often, of course, several motives have led to an individual study. Whatever the initial reasons for these studies, however, they are leading to an increased understanding of the general process of transport in renal tubules. In this review, I summarize the essential findings of these studies in regard to the transport of fluid, electrophysiology and the transport of inorganic ions, and the transport of organic substances. I attempt to indicate the particular importance of these findings for renal physiology, the way in which such findings are derived from the use of the isolated perfusion technique with the tubules from certain nonmammalian vertebrates, and the directions in which these studies are leading." @default.
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- W2040759600 date "1982-11-01" @default.
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- W2040759600 title "Studies on nonmammalian nephrons" @default.
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- W2040759600 doi "https://doi.org/10.1038/ki.1982.210" @default.
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