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- W2040761891 abstract "In PNAS, Nucci et al. (1) present an NMR study suggesting the pressure-induced denaturation of individual domains of the T4 lysozyme mutant Leu99Ala (T4L L99A). The denaturation equilibrium was considered to be responsible for the pressure-induced loss of 15N-1H heteronuclear single quantum coherence (HSQC) cross-peaks, which were preferentially observed for residues in the C-terminal domain. Independently, our laboratories have studied the L99A mutant by high-pressure NMR spectroscopy (2)." @default.
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- W2040761891 date "2015-01-28" @default.
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- W2040761891 title "Is pressure-induced signal loss in NMR spectra for the Leu99Ala cavity mutant of T4 lysozyme due to unfolding?" @default.
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- W2040761891 doi "https://doi.org/10.1073/pnas.1423279112" @default.
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