Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040767079> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2040767079 endingPage "737" @default.
- W2040767079 startingPage "733" @default.
- W2040767079 abstract "To compare the impact of CO2 laparoscopy, gasless laparoscopy, and midline laparotomy on the development of distant metastases and on survival in two ovarian carcinoma models.A prospective randomised study in rats.and methods Two ovarian cancer xenografts were obtained by intraperitoneal injection of IGR-OV1 or NIH-OVCAR-3 cells. Experimental surgical procedures were performed on day 7 (IGR-OVI model) or day 14 (NIH: OVCAR-3 model) after intraperitoneal injection: CO2 laparoscopy (pneumoperitoneum (PNP) with unheated CO2 at a pressure of 8 mmHg for 1 hour); gasless laparoscopy (consisting in abdominal wall expansion by a balloon for 1 hour); midline laparoscopy (consisting in bowel exteriorisation on a mesh for one hour following xyphopubic laparotomy). The control group underwent general anaesthesia alone. The animals were killed by CO2 inhalation as soon as they became moribund.Pathological examination was carried out on the liver, lungs and pleura as well as the retroperitoneal nodes. Survival was determined from the time of surgery to the sacrifice of the animal. Statistical analysis used ANOVA, Fisher exact test, Bonferonni method and the log-rank test.In the IGR-OV1 model, distant metastases were rare, and were not promoted by CO2 laparoscopy. With the NIH: OVCAR-3 model, pleural, pulmonary and para-aortic metastases were not enhanced by CO2 PNP when compared with other approaches. Conversely, midline laparotomy and laparoscopy significantly increased liver involvement when compared with gasless laparoscopy (P = 0.04 and P = 0.008). Survival was comparable no matter what kind of surgery had been performed in the IGR-OV1 model (P = 0.7) or in the NIH: OVCAR-3 model (P = 0.5).CO2 laparoscopy had a minor impact on distant and nodal metastases in the two models. Similarly, survival was similar for all surgical groups." @default.
- W2040767079 created "2016-06-24" @default.
- W2040767079 creator A5002637458 @default.
- W2040767079 creator A5009542208 @default.
- W2040767079 creator A5044828953 @default.
- W2040767079 creator A5057065462 @default.
- W2040767079 creator A5060116556 @default.
- W2040767079 creator A5060565441 @default.
- W2040767079 creator A5083329331 @default.
- W2040767079 creator A5089962133 @default.
- W2040767079 date "2001-07-01" @default.
- W2040767079 modified "2023-09-22" @default.
- W2040767079 title "Impact of pneumoperitoneum on visceral metastasis rate and survival. Results in two ovarian cancer models in rats" @default.
- W2040767079 cites W1967482370 @default.
- W2040767079 cites W1979756234 @default.
- W2040767079 cites W1980495382 @default.
- W2040767079 cites W2000273398 @default.
- W2040767079 cites W2012848460 @default.
- W2040767079 cites W2025901035 @default.
- W2040767079 cites W2035364405 @default.
- W2040767079 cites W2053114143 @default.
- W2040767079 cites W2065347296 @default.
- W2040767079 cites W4231422501 @default.
- W2040767079 cites W4239319191 @default.
- W2040767079 doi "https://doi.org/10.1111/j.1471-0528.2001.00135.x" @default.
- W2040767079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11467700" @default.
- W2040767079 hasPublicationYear "2001" @default.
- W2040767079 type Work @default.
- W2040767079 sameAs 2040767079 @default.
- W2040767079 citedByCount "5" @default.
- W2040767079 countsByYear W20407670792019 @default.
- W2040767079 crossrefType "journal-article" @default.
- W2040767079 hasAuthorship W2040767079A5002637458 @default.
- W2040767079 hasAuthorship W2040767079A5009542208 @default.
- W2040767079 hasAuthorship W2040767079A5044828953 @default.
- W2040767079 hasAuthorship W2040767079A5057065462 @default.
- W2040767079 hasAuthorship W2040767079A5060116556 @default.
- W2040767079 hasAuthorship W2040767079A5060565441 @default.
- W2040767079 hasAuthorship W2040767079A5083329331 @default.
- W2040767079 hasAuthorship W2040767079A5089962133 @default.
- W2040767079 hasConcept C121608353 @default.
- W2040767079 hasConcept C126322002 @default.
- W2040767079 hasConcept C141071460 @default.
- W2040767079 hasConcept C2778746874 @default.
- W2040767079 hasConcept C2780047204 @default.
- W2040767079 hasConcept C2780427987 @default.
- W2040767079 hasConcept C2780778865 @default.
- W2040767079 hasConcept C3019054536 @default.
- W2040767079 hasConcept C71924100 @default.
- W2040767079 hasConceptScore W2040767079C121608353 @default.
- W2040767079 hasConceptScore W2040767079C126322002 @default.
- W2040767079 hasConceptScore W2040767079C141071460 @default.
- W2040767079 hasConceptScore W2040767079C2778746874 @default.
- W2040767079 hasConceptScore W2040767079C2780047204 @default.
- W2040767079 hasConceptScore W2040767079C2780427987 @default.
- W2040767079 hasConceptScore W2040767079C2780778865 @default.
- W2040767079 hasConceptScore W2040767079C3019054536 @default.
- W2040767079 hasConceptScore W2040767079C71924100 @default.
- W2040767079 hasIssue "7" @default.
- W2040767079 hasLocation W20407670791 @default.
- W2040767079 hasLocation W20407670792 @default.
- W2040767079 hasOpenAccess W2040767079 @default.
- W2040767079 hasPrimaryLocation W20407670791 @default.
- W2040767079 hasRelatedWork W1775622553 @default.
- W2040767079 hasRelatedWork W2034275446 @default.
- W2040767079 hasRelatedWork W2040767079 @default.
- W2040767079 hasRelatedWork W2053320520 @default.
- W2040767079 hasRelatedWork W2151371638 @default.
- W2040767079 hasRelatedWork W2286476822 @default.
- W2040767079 hasRelatedWork W2347968763 @default.
- W2040767079 hasRelatedWork W2390961722 @default.
- W2040767079 hasRelatedWork W2415056006 @default.
- W2040767079 hasRelatedWork W4240763907 @default.
- W2040767079 hasVolume "108" @default.
- W2040767079 isParatext "false" @default.
- W2040767079 isRetracted "false" @default.
- W2040767079 magId "2040767079" @default.
- W2040767079 workType "article" @default.