Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040768048> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2040768048 endingPage "327" @default.
- W2040768048 startingPage "321" @default.
- W2040768048 abstract "Some studies have suggested reduced activity of clopidogrel on platelet activation and adherence in patients using statins.To assess whether platelet activation and aggregation decrease with clopidogrel, and whether there is a reduction of the action of clopidogrel when associated with atorvastatin or simvastatin.This prospective study included 68 patients with stable angina with previous use of simvastatin, atorvastatin, or no statin (control group), with previous elective indication of percutaneous coronary intervention (PCI). Platelet activation was analyzed by means of platelet count, levels of P-selectin and glycoprotein IIb/IIIa (with and without ADP stimulation) by flow cytometry. The findings were analyzed before and after percutaneous coronary intervention and the administration of clopidogrel.We observed reduction in platelet activity with use of clopidogrel. Furthermore, no differences were found between the variables analyzed to prove reduced activity of clopidogrel when combined with statins. We observed levels of p-selectin (pre-angioplasty: 14.23 ± 7.52 x 8.83 x 11.45 ± 7.65 ± 7.09; after angioplasty: 21.49 ± 23.82 x 4 37 ± 2.71 x 4.82 ± 4.47, ρ < 0.01) and glycoprotein IIb/IIIa (pre-angioplasty: 98.97 ± 0.43 ± 1.25 x 98.79 x 99.21 ± 0.40 after angioplasty: 99.37 ± 0.29 ± 1.47 x 98.50 x 98.92 ± 0.88, ρ = 0.52), respectively, in the control, atorvastatin and simvastatin groups.We concluded that platelet activation decreases with administration of clopidogrel, and clopidogrel has no antiplatelet effect reduced in the presence of simvastatin or atorvastatin." @default.
- W2040768048 created "2016-06-24" @default.
- W2040768048 creator A5002506097 @default.
- W2040768048 creator A5003752960 @default.
- W2040768048 creator A5010466306 @default.
- W2040768048 creator A5040821725 @default.
- W2040768048 creator A5041395774 @default.
- W2040768048 creator A5044814738 @default.
- W2040768048 creator A5058917462 @default.
- W2040768048 creator A5068140364 @default.
- W2040768048 creator A5073960839 @default.
- W2040768048 date "2010-09-01" @default.
- W2040768048 modified "2023-09-23" @default.
- W2040768048 title "Ausência de interação clopidogrel-estatina em pacientes submetidos a implante de stent coronário" @default.
- W2040768048 cites W1415139109 @default.
- W2040768048 cites W1552261360 @default.
- W2040768048 cites W1553345686 @default.
- W2040768048 cites W1952796400 @default.
- W2040768048 cites W1974238774 @default.
- W2040768048 cites W1991816791 @default.
- W2040768048 cites W2017501956 @default.
- W2040768048 cites W2038463104 @default.
- W2040768048 cites W2046852461 @default.
- W2040768048 cites W2067654607 @default.
- W2040768048 cites W2072308694 @default.
- W2040768048 cites W2083038715 @default.
- W2040768048 cites W2101913445 @default.
- W2040768048 cites W21063540 @default.
- W2040768048 cites W2125348077 @default.
- W2040768048 cites W2133006990 @default.
- W2040768048 cites W2139473713 @default.
- W2040768048 cites W2149238031 @default.
- W2040768048 cites W2152890478 @default.
- W2040768048 cites W2159999748 @default.
- W2040768048 cites W2167873388 @default.
- W2040768048 cites W2201082669 @default.
- W2040768048 cites W2611749980 @default.
- W2040768048 cites W2162886638 @default.
- W2040768048 cites W3196281524 @default.
- W2040768048 doi "https://doi.org/10.1590/s0066-782x2010005000106" @default.
- W2040768048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20721515" @default.
- W2040768048 hasPublicationYear "2010" @default.
- W2040768048 type Work @default.
- W2040768048 sameAs 2040768048 @default.
- W2040768048 citedByCount "5" @default.
- W2040768048 countsByYear W20407680482012 @default.
- W2040768048 countsByYear W20407680482013 @default.
- W2040768048 countsByYear W20407680482015 @default.
- W2040768048 crossrefType "journal-article" @default.
- W2040768048 hasAuthorship W2040768048A5002506097 @default.
- W2040768048 hasAuthorship W2040768048A5003752960 @default.
- W2040768048 hasAuthorship W2040768048A5010466306 @default.
- W2040768048 hasAuthorship W2040768048A5040821725 @default.
- W2040768048 hasAuthorship W2040768048A5041395774 @default.
- W2040768048 hasAuthorship W2040768048A5044814738 @default.
- W2040768048 hasAuthorship W2040768048A5058917462 @default.
- W2040768048 hasAuthorship W2040768048A5068140364 @default.
- W2040768048 hasAuthorship W2040768048A5073960839 @default.
- W2040768048 hasBestOaLocation W20407680481 @default.
- W2040768048 hasConcept C126322002 @default.
- W2040768048 hasConcept C2777628954 @default.
- W2040768048 hasConcept C2777849778 @default.
- W2040768048 hasConcept C29456083 @default.
- W2040768048 hasConcept C71924100 @default.
- W2040768048 hasConceptScore W2040768048C126322002 @default.
- W2040768048 hasConceptScore W2040768048C2777628954 @default.
- W2040768048 hasConceptScore W2040768048C2777849778 @default.
- W2040768048 hasConceptScore W2040768048C29456083 @default.
- W2040768048 hasConceptScore W2040768048C71924100 @default.
- W2040768048 hasIssue "3" @default.
- W2040768048 hasLocation W20407680481 @default.
- W2040768048 hasLocation W20407680482 @default.
- W2040768048 hasLocation W20407680483 @default.
- W2040768048 hasLocation W20407680484 @default.
- W2040768048 hasOpenAccess W2040768048 @default.
- W2040768048 hasPrimaryLocation W20407680481 @default.
- W2040768048 hasRelatedWork W1965650618 @default.
- W2040768048 hasRelatedWork W1983829728 @default.
- W2040768048 hasRelatedWork W2039007691 @default.
- W2040768048 hasRelatedWork W2100209758 @default.
- W2040768048 hasRelatedWork W2236042039 @default.
- W2040768048 hasRelatedWork W2530971435 @default.
- W2040768048 hasRelatedWork W2810359251 @default.
- W2040768048 hasRelatedWork W3134665543 @default.
- W2040768048 hasRelatedWork W3135788989 @default.
- W2040768048 hasRelatedWork W4251140430 @default.
- W2040768048 hasVolume "95" @default.
- W2040768048 isParatext "false" @default.
- W2040768048 isRetracted "false" @default.
- W2040768048 magId "2040768048" @default.
- W2040768048 workType "article" @default.