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- W2040771856 abstract "The first-line evaluation of aortic stenosis severity is Doppler echocardiography. However, in up to 40% of patients, resting echocardiographic assessment of aortic stenosis severity is discordant, leading to clinical uncertainty. Interest has therefore grown in aortic valve calcium scoring by multidetector computed tomography (CT-AVC) as an alternative load independent assessment of aortic stenosis severity. This paper will briefly review the pathophysiology of aortic stenosis and the crucial role that calcification plays in driving progressive obstruction of the valve. Subsequently, it will describe published reports that have investigated CT-AVC, validating this parameter against histology, and establishing its diagnostic accuracy versus echocardiography as well as its powerful independent prognostic capability. Finally, this review seeks to provide a practical guide about how best to acquire and interpret CT-AVC with a close focus on potential pitfalls and how these might be best avoided as this technique becomes more widely adopted in to clinical practice." @default.
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- W2040771856 date "1991-06-01" @default.
- W2040771856 modified "2023-09-24" @default.
- W2040771856 title "Massive calcification of a porcine bioprosthesis in the aortic valve position and the role of calcium supplements" @default.
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- W2040771856 doi "https://doi.org/10.1016/0002-8703(91)90042-g" @default.
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