FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040773907> ?p ?o ?g. }

• W2040773907 endingPage "117" @default.
• W2040773907 startingPage "111" @default.
• W2040773907 abstract "At present, through public awareness and the use of improved diagnostic aids, increasing numbers of patients are being seen with localized “minimal” breast cancer. In our own experience, the average measured size of the primary tumor has diminished from 3.2 cm in 1955 to 2 cm in 1974. Although the incidence of axillary node metastases has diminished only from about 50% to 42% during this interval, the extent of involvement and the distribution of nodal disease has improved markedly with a marked decrease in apical node involvement. Mammography has been responsible for the detection of more than 50% of our “minimal” breast cancers. This improved patient material presents a great potential for improved control of this disease. In planning the choice of surgery for primary breast cancer, its multicentric origin, and regional nodal spread to axillary and internal mammary nodal areas must be considered. There is no single ideal operation for all breast cancers. The scope of surgery should be correlated with the clinical and pathologic extent of disease in the individual patient with the aim of removing all disease present while preserving appearance and function—the main goal being removal of disease. We have utilized three operative procedures: total mastectomy with axillary dissection, radical mastectomy, and extended radical mastectomy. With this approach a 10-year survival rate of 61% with a local recurrence rate of 7.7% has been attained in a group of 565 patients with 40% axillary node involvement. The best salvage obtained in patients with “minimal” breast cancers—noninfiltrating cancers and infiltrating cancers under 1 cm in diameter with clinically negative axillae—was 95% survival at 10 years following modified radical mastectomy (total mastectomy with axillary dissection). When disease has extended to the axillary nodes the more extensive procedures have proved more effective in achieving long term control—54% 10 year survival in patients with axillary node metastases treated by the extended radical mastectomy. An increasing number of patients are being seen who can be treated adequately by less than a radical mastectomy. Careful clinical judgment and close liason with a competent pathologist must be combined in selecting the proper operative procedure for each individual patient. Statistics concerning therapeutic effects based on current material, unless they are based on accurate data covering extent of disease, cannot be compared with previous data because of the improved patient material now being encountered. Adjuvant multiple chemotherapy appears promising as a supplement to surgical treatment of breast cancer. However, it should not be used to replace or minimize the role of primary surgery, but should be combined with the optimum procedure for each individual patient." @default.
• W2040773907 created "2016-06-24" @default.
• W2040773907 creator A5022969743 @default.
• W2040773907 date "1976-01-01" @default.
• W2040773907 modified "2023-09-24" @default.
• W2040773907 title "Changing patterns of breast cancer. Lucy Wortham James lecture (clinical)" @default.
• W2040773907 cites W1981068733 @default.
• W2040773907 cites W1981608369 @default.
• W2040773907 cites W1995332533 @default.
• W2040773907 cites W2002540677 @default.
• W2040773907 cites W2011907057 @default.
• W2040773907 cites W2014281161 @default.
• W2040773907 cites W2036802856 @default.
• W2040773907 cites W2049082433 @default.
• W2040773907 cites W2060004056 @default.
• W2040773907 cites W2067150358 @default.
• W2040773907 cites W2069930757 @default.
• W2040773907 cites W2095447586 @default.
• W2040773907 cites W2124321631 @default.
• W2040773907 cites W2124432914 @default.
• W2040773907 cites W2418779805 @default.
• W2040773907 doi "https://doi.org/10.1002/1097-0142(197601)37:1<111::aid-cncr2820370117>3.0.co;2-k" @default.
• W2040773907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1247947" @default.
• W2040773907 hasPublicationYear "1976" @default.
• W2040773907 type Work @default.
• W2040773907 sameAs 2040773907 @default.
• W2040773907 citedByCount "34" @default.
• W2040773907 crossrefType "journal-article" @default.
• W2040773907 hasAuthorship W2040773907A5022969743 @default.
• W2040773907 hasConcept C121608353 @default.
• W2040773907 hasConcept C126322002 @default.
• W2040773907 hasConcept C141071460 @default.
• W2040773907 hasConcept C143998085 @default.
• W2040773907 hasConcept C2776608951 @default.
• W2040773907 hasConcept C2777757722 @default.
• W2040773907 hasConcept C2779134260 @default.
• W2040773907 hasConcept C2780404832 @default.
• W2040773907 hasConcept C2780472235 @default.
• W2040773907 hasConcept C2780849966 @default.
• W2040773907 hasConcept C2910733956 @default.
• W2040773907 hasConcept C530470458 @default.
• W2040773907 hasConcept C71924100 @default.
• W2040773907 hasConceptScore W2040773907C121608353 @default.
• W2040773907 hasConceptScore W2040773907C126322002 @default.
• W2040773907 hasConceptScore W2040773907C141071460 @default.
• W2040773907 hasConceptScore W2040773907C143998085 @default.
• W2040773907 hasConceptScore W2040773907C2776608951 @default.
• W2040773907 hasConceptScore W2040773907C2777757722 @default.
• W2040773907 hasConceptScore W2040773907C2779134260 @default.
• W2040773907 hasConceptScore W2040773907C2780404832 @default.
• W2040773907 hasConceptScore W2040773907C2780472235 @default.
• W2040773907 hasConceptScore W2040773907C2780849966 @default.
• W2040773907 hasConceptScore W2040773907C2910733956 @default.
• W2040773907 hasConceptScore W2040773907C530470458 @default.
• W2040773907 hasConceptScore W2040773907C71924100 @default.
• W2040773907 hasIssue "1" @default.
• W2040773907 hasLocation W20407739071 @default.
• W2040773907 hasLocation W20407739072 @default.
• W2040773907 hasOpenAccess W2040773907 @default.
• W2040773907 hasPrimaryLocation W20407739071 @default.
• W2040773907 hasRelatedWork W1999807988 @default.
• W2040773907 hasRelatedWork W2034400487 @default.
• W2040773907 hasRelatedWork W2038436195 @default.
• W2040773907 hasRelatedWork W2041939897 @default.
• W2040773907 hasRelatedWork W2055058004 @default.
• W2040773907 hasRelatedWork W2412203384 @default.
• W2040773907 hasRelatedWork W2414154311 @default.
• W2040773907 hasRelatedWork W2414431919 @default.
• W2040773907 hasRelatedWork W2415988967 @default.
• W2040773907 hasRelatedWork W2759031936 @default.
• W2040773907 hasVolume "37" @default.
• W2040773907 isParatext "false" @default.
• W2040773907 isRetracted "false" @default.
• W2040773907 magId "2040773907" @default.
• W2040773907 workType "article" @default.