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- W2040776003 abstract "Summary. We report a case of therapy‐related myelodysplastic syndrome (t‐MDS) with t(10;16)(q22;p13), in which novel fusion transcripts of the MORF and CBP genes were detected. In one MORF–CBP fusion transcript, exon 15 of the MORF gene was fused in frame with exon 5 of the CBP gene. In a reciprocal CBP–MORF transcript, exon 4 of the CBP gene was fused in frame with exon 16 of the MORF gene. This is the first reported case of t‐MDS associated with t(10;16), and provides molecular evidence that the novel MORF–CBP and/or CBP–MORF fusion protein(s) might play an important role in the development of t‐MDS." @default.
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- W2040776003 date "2003-01-01" @default.
- W2040776003 modified "2023-10-17" @default.
- W2040776003 title "A novel fusion variant of the <i>MORF</i> and <i>CBP</i> genes detected in therapy-related myelodysplastic syndrome with t(10;16)(q22;p13)" @default.
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- W2040776003 doi "https://doi.org/10.1046/j.1365-2141.2003.04059.x" @default.
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