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• W2040776883 startingPage "1767" @default.
• W2040776883 abstract "Abstract Tissue‐engineered nerve guides can provide mechanical support as well as chemical stimulation for nerve regeneration. PC12 cells were used to test the novel combination of poly(caprolactone) (PCL) and macroporous collagen‐based microcarriers (CultiSphers) as an initial phase in the fabrication of multichanneled nerve guides. Laminin‐coated PCL was an effective matrix for the attachment, proliferation, and viability of PC12 cells, relative to uncoated PCL. PC12 cells attached to laminin‐coated PCL and extended neurites when cultured in the presence of nerve growth factor (NGF). PC12 cells attached and proliferated on CultiSphers and extended neurites in response to NGF. A novel PCL/CultiSpher composite material also supported PC12 attachment and proliferation and provides a potentially useful material for the fabrication of synthetic nerve guides." @default.
• W2040776883 created "2016-06-24" @default.
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• W2040776883 date "2003-01-01" @default.
• W2040776883 modified "2023-10-18" @default.
• W2040776883 title "Using PC12 Cells To Evaluate Poly(caprolactone) and Collagenous Microcarriers for Applications in Nerve Guide Fabrication" @default.
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• W2040776883 doi "https://doi.org/10.1021/bp034086m" @default.
• W2040776883 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14656154" @default.
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