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• W2040783773 abstract "Lysophosphatidylcholine (lyso‐PC) accumulates in tissues undergoing inflammation and atherosclerosis, where an infiltration of T cells is also seen. We found that lyso‐PC increased IFN‐γ production and CD40L expression in CD4+ T cells stimulated with anti‐CD3 Ab and recombinant CD80 molecules, whereas lyso‐PC did not affect IL‐2 and IL‐4 production. These results suggest that lyso‐PC, in combination with other stimuli, may regulate CD4+ T cell functions to propagate local inflammatory reactions and also imply a novel role played by a modified lipid in the selection of Th1/Th2 immune response as well as in the T cell mediated pathogenesis in atherosclerosis." @default.
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• W2040783773 date "1998-08-14" @default.
• W2040783773 modified "2023-09-27" @default.
• W2040783773 title "Lysophosphatidylcholine upregulates CD40 ligand expression in newly activated human CD4+ T cells" @default.
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• W2040783773 doi "https://doi.org/10.1016/s0014-5793(98)00898-9" @default.
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