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- W2040785589 abstract "Purpose: Anorexia is a common symptom in terminal cancer patients. Some data have suggested a role of visfatin in regulating feeding behavior. We studied the relationship of a serum visfatin level and anorexia in cancer patients provided with hospice care. Methods: After informed consent was obtained, 69 cancer patients over 20 years old at a hospice center were enrolled in the study from July 2009 t o July 2010. We characterized patients by age, sex, body mass index, primary cancer site, and Eastern Cooperat ive Oncology Group (ECOG) performance status, etc. Also, blood tests were performed to measure the level of h emoglobin, white blood cell (WBC), C-reactive protein (CRP), total cholesterol, albumin, lymphocyte count, glucose, blood urea nitrogen (BUN), creatinine, tumor necrosis factor-alpha (TNF-α), interukin-6, leptin and visfatin. Results: The mean age of subjects was 65.5 years old, According to univariate analysis, pulse, ECOG performance scale, opioid use and visfatin level were different between the anorexia and non-anorexic group (P<0.05). The media n visfatin level was higher in the anorexia group than the good appetite group (P=0.0323). Serum visfatin concentrations were not related with either body mass index or serum leptin or total cholesterol levels, but it was negatively correlated with serum albumin levels (P=0.0198) and lymphocyte counts (P=0.0013). Conclusion: This study did not identify a novel link between visfatin levels and anorexia in cancer patients at a hospice." @default.
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- W2040785589 date "2014-03-01" @default.
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- W2040785589 title "The Relationship of Plasma Visfatin Level and Anorexia in Terminal Cancer Patients" @default.
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- W2040785589 doi "https://doi.org/10.14475/kjhpc.2014.17.1.18" @default.
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