Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040785951> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2040785951 endingPage "161" @default.
- W2040785951 startingPage "149" @default.
- W2040785951 abstract "AbstractFour xanthene derivatives, namely, 8-chlorotheophylline, caffeine, theophylline and 1-methyl-3-sisobutylxanthene (SC-2964) were studied to ascertain their in vitro intestinal absorbability and partitioning property in an octyl alcohol/pH 7.4 buffer system. Absorbability in vitro was estimated as the cumulative transfer rate (μglmin.) of the test compounds transfering across everted rat intestine sacs. The results demonstrated a dependency of the cumulative transfer rates on the partition coefficients. A logarithmic correlation between cumulative transfer rates and partition coefficients of the test compounds was observed. It is concluded that this predictive methodology could be adopted to screen potentially active compounds and optimize the selection of compounds to be developed into orally bioavailable dosage forms." @default.
- W2040785951 created "2016-06-24" @default.
- W2040785951 creator A5036993620 @default.
- W2040785951 creator A5039607173 @default.
- W2040785951 creator A5091912806 @default.
- W2040785951 date "1977-01-01" @default.
- W2040785951 modified "2023-09-30" @default.
- W2040785951 title "Relationship Between in vitro Intestinal Absorbability and Partition Coefficients of Xanthene Derivatives" @default.
- W2040785951 cites W1983180901 @default.
- W2040785951 cites W2001825651 @default.
- W2040785951 cites W2004762518 @default.
- W2040785951 cites W2021472207 @default.
- W2040785951 cites W2052008210 @default.
- W2040785951 cites W2052389363 @default.
- W2040785951 cites W2067468321 @default.
- W2040785951 cites W2091362207 @default.
- W2040785951 cites W2166876945 @default.
- W2040785951 cites W2207129414 @default.
- W2040785951 cites W2516850296 @default.
- W2040785951 doi "https://doi.org/10.3109/03639047709051921" @default.
- W2040785951 hasPublicationYear "1977" @default.
- W2040785951 type Work @default.
- W2040785951 sameAs 2040785951 @default.
- W2040785951 citedByCount "7" @default.
- W2040785951 countsByYear W20407859512015 @default.
- W2040785951 crossrefType "journal-article" @default.
- W2040785951 hasAuthorship W2040785951A5036993620 @default.
- W2040785951 hasAuthorship W2040785951A5039607173 @default.
- W2040785951 hasAuthorship W2040785951A5091912806 @default.
- W2040785951 hasConcept C134018914 @default.
- W2040785951 hasConcept C178790620 @default.
- W2040785951 hasConcept C181389837 @default.
- W2040785951 hasConcept C185592680 @default.
- W2040785951 hasConcept C192552737 @default.
- W2040785951 hasConcept C202751555 @default.
- W2040785951 hasConcept C2777363021 @default.
- W2040785951 hasConcept C2778095195 @default.
- W2040785951 hasConcept C2778500429 @default.
- W2040785951 hasConcept C43617362 @default.
- W2040785951 hasConcept C55493867 @default.
- W2040785951 hasConcept C86803240 @default.
- W2040785951 hasConcept C98274493 @default.
- W2040785951 hasConceptScore W2040785951C134018914 @default.
- W2040785951 hasConceptScore W2040785951C178790620 @default.
- W2040785951 hasConceptScore W2040785951C181389837 @default.
- W2040785951 hasConceptScore W2040785951C185592680 @default.
- W2040785951 hasConceptScore W2040785951C192552737 @default.
- W2040785951 hasConceptScore W2040785951C202751555 @default.
- W2040785951 hasConceptScore W2040785951C2777363021 @default.
- W2040785951 hasConceptScore W2040785951C2778095195 @default.
- W2040785951 hasConceptScore W2040785951C2778500429 @default.
- W2040785951 hasConceptScore W2040785951C43617362 @default.
- W2040785951 hasConceptScore W2040785951C55493867 @default.
- W2040785951 hasConceptScore W2040785951C86803240 @default.
- W2040785951 hasConceptScore W2040785951C98274493 @default.
- W2040785951 hasIssue "2" @default.
- W2040785951 hasLocation W20407859511 @default.
- W2040785951 hasOpenAccess W2040785951 @default.
- W2040785951 hasPrimaryLocation W20407859511 @default.
- W2040785951 hasRelatedWork W1545184655 @default.
- W2040785951 hasRelatedWork W1968362740 @default.
- W2040785951 hasRelatedWork W2024118935 @default.
- W2040785951 hasRelatedWork W2054440930 @default.
- W2040785951 hasRelatedWork W2054447553 @default.
- W2040785951 hasRelatedWork W2056059084 @default.
- W2040785951 hasRelatedWork W2078915905 @default.
- W2040785951 hasRelatedWork W2083588958 @default.
- W2040785951 hasRelatedWork W2085021668 @default.
- W2040785951 hasRelatedWork W2170494490 @default.
- W2040785951 hasVolume "3" @default.
- W2040785951 isParatext "false" @default.
- W2040785951 isRetracted "false" @default.
- W2040785951 magId "2040785951" @default.
- W2040785951 workType "article" @default.