FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040803520> ?p ?o ?g. }

• W2040803520 endingPage "13185" @default.
• W2040803520 startingPage "13180" @default.
• W2040803520 abstract "Members of the myc family of nuclear protooncogenes play roles in cell proliferation, differentiation, and apoptosis. Moreover, inappropriate expression of c- myc genes contributes to the development of many types of cancers, including B cell lymphomas in humans. Although Myc proteins have been shown to function as transcription factors, their immediate effects on the cell have not been well defined. Here we have utilized a murine model of lymphomagenesis (Eμ- myc mice) to show that constitutive expression of a c- myc transgene under control of the Ig heavy-chain enhancer (Eμ) results in an increase in cell size of normal pretransformed B lymphocytes at all stages of B cell development. Furthermore, we show that c-Myc-induced growth occurs independently of cell cycle phase and correlates with an increase in protein synthesis. These results suggest that Myc may normally function by coordinating expression of growth-related genes in response to mitogenic signals. Deregulated c- myc expression may predispose to cancer by enhancing cell growth to levels required for unrestrained cell division." @default.
• W2040803520 created "2016-06-24" @default.
• W2040803520 creator A5048512973 @default.
• W2040803520 creator A5082542184 @default.
• W2040803520 date "1999-11-09" @default.
• W2040803520 modified "2023-10-11" @default.
• W2040803520 title "c-Myc enhances protein synthesis and cell size during B lymphocyte development" @default.
• W2040803520 cites W107691157 @default.
• W2040803520 cites W128302075 @default.
• W2040803520 cites W137827881 @default.
• W2040803520 cites W1412788771 @default.
• W2040803520 cites W1491528256 @default.
• W2040803520 cites W1499561084 @default.
• W2040803520 cites W1507446938 @default.
• W2040803520 cites W1509850974 @default.
• W2040803520 cites W1546589729 @default.
• W2040803520 cites W155748415 @default.
• W2040803520 cites W1579450536 @default.
• W2040803520 cites W1590458072 @default.
• W2040803520 cites W161464813 @default.
• W2040803520 cites W1847174723 @default.
• W2040803520 cites W1853273344 @default.
• W2040803520 cites W1942629554 @default.
• W2040803520 cites W1968075576 @default.
• W2040803520 cites W1968710429 @default.
• W2040803520 cites W1975489321 @default.
• W2040803520 cites W1977289089 @default.
• W2040803520 cites W1977290507 @default.
• W2040803520 cites W1977895957 @default.
• W2040803520 cites W1984063704 @default.
• W2040803520 cites W1989461823 @default.
• W2040803520 cites W2007021266 @default.
• W2040803520 cites W2010379212 @default.
• W2040803520 cites W2011330893 @default.
• W2040803520 cites W2015815772 @default.
• W2040803520 cites W2021253208 @default.
• W2040803520 cites W2025313392 @default.
• W2040803520 cites W2029922809 @default.
• W2040803520 cites W2034442000 @default.
• W2040803520 cites W2035820068 @default.
• W2040803520 cites W2037586575 @default.
• W2040803520 cites W2042777921 @default.
• W2040803520 cites W2049114614 @default.
• W2040803520 cites W2050563044 @default.
• W2040803520 cites W2059427680 @default.
• W2040803520 cites W2069501059 @default.
• W2040803520 cites W2073386386 @default.
• W2040803520 cites W2074301593 @default.
• W2040803520 cites W2083068671 @default.
• W2040803520 cites W2085841899 @default.
• W2040803520 cites W2088665501 @default.
• W2040803520 cites W2096462919 @default.
• W2040803520 cites W2097774235 @default.
• W2040803520 cites W2104014517 @default.
• W2040803520 cites W2104788426 @default.
• W2040803520 cites W2122346633 @default.
• W2040803520 cites W2131971400 @default.
• W2040803520 cites W2140052138 @default.
• W2040803520 cites W2154546525 @default.
• W2040803520 cites W2163307259 @default.
• W2040803520 cites W2164515753 @default.
• W2040803520 cites W2165271479 @default.
• W2040803520 cites W2259715529 @default.
• W2040803520 cites W2342019498 @default.
• W2040803520 cites W2418896639 @default.
• W2040803520 cites W37384269 @default.
• W2040803520 cites W4236512674 @default.
• W2040803520 cites W4238649740 @default.
• W2040803520 cites W4241495518 @default.
• W2040803520 doi "https://doi.org/10.1073/pnas.96.23.13180" @default.
• W2040803520 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/23921" @default.
• W2040803520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10557294" @default.
• W2040803520 hasPublicationYear "1999" @default.
• W2040803520 type Work @default.
• W2040803520 sameAs 2040803520 @default.
• W2040803520 citedByCount "327" @default.
• W2040803520 countsByYear W20408035202012 @default.
• W2040803520 countsByYear W20408035202013 @default.
• W2040803520 countsByYear W20408035202014 @default.
• W2040803520 countsByYear W20408035202015 @default.
• W2040803520 countsByYear W20408035202016 @default.
• W2040803520 countsByYear W20408035202017 @default.
• W2040803520 countsByYear W20408035202018 @default.
• W2040803520 countsByYear W20408035202019 @default.
• W2040803520 countsByYear W20408035202020 @default.
• W2040803520 countsByYear W20408035202021 @default.
• W2040803520 countsByYear W20408035202022 @default.
• W2040803520 countsByYear W20408035202023 @default.
• W2040803520 crossrefType "journal-article" @default.
• W2040803520 hasAuthorship W2040803520A5048512973 @default.
• W2040803520 hasAuthorship W2040803520A5082542184 @default.
• W2040803520 hasBestOaLocation W20408035201 @default.
• W2040803520 hasConcept C102230213 @default.
• W2040803520 hasConcept C104317684 @default.
• W2040803520 hasConcept C111936080 @default.
• W2040803520 hasConcept C1491633281 @default.
• W2040803520 hasConcept C150194340 @default.
• W2040803520 hasConcept C153911025 @default.

• next