Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040806564> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2040806564 endingPage "343" @default.
- W2040806564 startingPage "332" @default.
- W2040806564 abstract "Background: In vitro studies of cefditoren activity have focused primarily on Streptococcus pneumoniae and other bacterial species isolated from patients with respiratory infections, but relatively few reports have been published describing the activity of cefditoren against clinical isolates of nonpneumococcal streptococci. Methods: Cefditoren activity was determined by broth microdilution (M7-A5, NCCLS, 2000) for 450 viridans group streptococci, 917 Streptococcus pyogenes and 800 other β-hemolytic streptococci collected throughout the US during 1999–2000. Results: Against viridans group streptococci, cefditoren (MIC90, 0.5 µg/ml) was 4- to 32-fold more active than the other β-lactams tested (penicillin ampicillin, amoxicillin-clavulanate, cefprozil and cefuroxime). The difference in activity between cefditoren and the other β-lactams was greater for penicillin-nonsusceptible isolates (MIC90s, 1 µg/ml versus 8–32 µg/ml) than among penicillin-susceptible isolates (MIC90s, 0.12 versus 0.25– 1 µg/ml). Cefditoren also demonstrated potent activity against S. pyogenes (MIC90, 0.015 µg/ml) and other β-hemolytic streptococci (MIC90, 0.06 µg/ml), comparable to that of the other β-lactams. Conclusions: The activity demonstrated by cefditoren against nonpneumococcal streptococci, including β-lactam- and macrolide-resistant isolates, suggests that this agent holds promise as therapy for infections caused by all clinically significant species of streptococci." @default.
- W2040806564 created "2016-06-24" @default.
- W2040806564 creator A5036530914 @default.
- W2040806564 creator A5038009031 @default.
- W2040806564 creator A5038353955 @default.
- W2040806564 creator A5059192444 @default.
- W2040806564 creator A5061522332 @default.
- W2040806564 creator A5063814702 @default.
- W2040806564 creator A5091128796 @default.
- W2040806564 date "2001-01-01" @default.
- W2040806564 modified "2023-09-27" @default.
- W2040806564 title "Comparative Activity of Cefditoren and Other Oral β-Lactams against Nonpneumococcal Streptococci" @default.
- W2040806564 cites W1894225655 @default.
- W2040806564 cites W1936862767 @default.
- W2040806564 cites W2000738597 @default.
- W2040806564 cites W2028402527 @default.
- W2040806564 cites W2030723239 @default.
- W2040806564 cites W2050631127 @default.
- W2040806564 cites W2062195998 @default.
- W2040806564 cites W2075430448 @default.
- W2040806564 cites W2122923319 @default.
- W2040806564 cites W2133017045 @default.
- W2040806564 cites W2133017406 @default.
- W2040806564 cites W2146993729 @default.
- W2040806564 cites W2148052607 @default.
- W2040806564 cites W2159216805 @default.
- W2040806564 cites W2416450701 @default.
- W2040806564 doi "https://doi.org/10.1159/000048540" @default.
- W2040806564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11561135" @default.
- W2040806564 hasPublicationYear "2001" @default.
- W2040806564 type Work @default.
- W2040806564 sameAs 2040806564 @default.
- W2040806564 citedByCount "4" @default.
- W2040806564 crossrefType "journal-article" @default.
- W2040806564 hasAuthorship W2040806564A5036530914 @default.
- W2040806564 hasAuthorship W2040806564A5038009031 @default.
- W2040806564 hasAuthorship W2040806564A5038353955 @default.
- W2040806564 hasAuthorship W2040806564A5059192444 @default.
- W2040806564 hasAuthorship W2040806564A5061522332 @default.
- W2040806564 hasAuthorship W2040806564A5063814702 @default.
- W2040806564 hasAuthorship W2040806564A5091128796 @default.
- W2040806564 hasConcept C174802600 @default.
- W2040806564 hasConcept C176947019 @default.
- W2040806564 hasConcept C2775897432 @default.
- W2040806564 hasConcept C2776021129 @default.
- W2040806564 hasConcept C2777514703 @default.
- W2040806564 hasConcept C2778276568 @default.
- W2040806564 hasConcept C2779306812 @default.
- W2040806564 hasConcept C2779489039 @default.
- W2040806564 hasConcept C2779708577 @default.
- W2040806564 hasConcept C2780950330 @default.
- W2040806564 hasConcept C2781253189 @default.
- W2040806564 hasConcept C501593827 @default.
- W2040806564 hasConcept C523546767 @default.
- W2040806564 hasConcept C54355233 @default.
- W2040806564 hasConcept C86803240 @default.
- W2040806564 hasConcept C89423630 @default.
- W2040806564 hasConceptScore W2040806564C174802600 @default.
- W2040806564 hasConceptScore W2040806564C176947019 @default.
- W2040806564 hasConceptScore W2040806564C2775897432 @default.
- W2040806564 hasConceptScore W2040806564C2776021129 @default.
- W2040806564 hasConceptScore W2040806564C2777514703 @default.
- W2040806564 hasConceptScore W2040806564C2778276568 @default.
- W2040806564 hasConceptScore W2040806564C2779306812 @default.
- W2040806564 hasConceptScore W2040806564C2779489039 @default.
- W2040806564 hasConceptScore W2040806564C2779708577 @default.
- W2040806564 hasConceptScore W2040806564C2780950330 @default.
- W2040806564 hasConceptScore W2040806564C2781253189 @default.
- W2040806564 hasConceptScore W2040806564C501593827 @default.
- W2040806564 hasConceptScore W2040806564C523546767 @default.
- W2040806564 hasConceptScore W2040806564C54355233 @default.
- W2040806564 hasConceptScore W2040806564C86803240 @default.
- W2040806564 hasConceptScore W2040806564C89423630 @default.
- W2040806564 hasIssue "5" @default.
- W2040806564 hasLocation W20408065641 @default.
- W2040806564 hasLocation W20408065642 @default.
- W2040806564 hasOpenAccess W2040806564 @default.
- W2040806564 hasPrimaryLocation W20408065641 @default.
- W2040806564 hasRelatedWork W1787743473 @default.
- W2040806564 hasRelatedWork W1996357595 @default.
- W2040806564 hasRelatedWork W2040806564 @default.
- W2040806564 hasRelatedWork W2046351437 @default.
- W2040806564 hasRelatedWork W2062377152 @default.
- W2040806564 hasRelatedWork W2071154764 @default.
- W2040806564 hasRelatedWork W2073042143 @default.
- W2040806564 hasRelatedWork W2102693859 @default.
- W2040806564 hasRelatedWork W2105253614 @default.
- W2040806564 hasRelatedWork W2298161860 @default.
- W2040806564 hasVolume "47" @default.
- W2040806564 isParatext "false" @default.
- W2040806564 isRetracted "false" @default.
- W2040806564 magId "2040806564" @default.
- W2040806564 workType "article" @default.