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- W2040806801 abstract "A method is presented for conveniently tritiating the aryl methyl sulfones of compounds identified as potent and selective inhibitors of human Cox-2 and as DP receptor antagonists. A base-catalyzed exchange reaction was conducted with deuterated water and the total deuterium incorporation, ranging from 46 to 99%, was calculated using mass spectrometry. Results from these exchanges were used as guidelines for tritium labeling giving specific radioactivities in the range of 28–120 mCi/mmol (1.03–4.43 GBq/mmol). Copyright © 2004 John Wiley & Sons, Ltd." @default.
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- W2040806801 date "2004-10-19" @default.
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- W2040806801 title "Base-catalyzed deuterium and tritium labeling of aryl methyl sulfones" @default.
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- W2040806801 doi "https://doi.org/10.1002/jlcr.880" @default.
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