FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040809972> ?p ?o ?g. }

• W2040809972 endingPage "151" @default.
• W2040809972 startingPage "145" @default.
• W2040809972 abstract "Human cytomegalovirus (HCMV) causes a highly prevalent and lifelong infection, with a multifaceted impact in human health. NK cells play an important role in the immune response to HCMV and the virus has reciprocally developed a variety of immune evasion strategies. We originally reported that HCMV infection promotes, to a variable degree in healthy individuals, a redistribution of the NK-cell receptor (NKR) repertoire which persists under steady-state conditions. Its hallmark is an expansion of a mature NK-cell subset displaying high surface levels of the CD94/NKG2C activating receptor, with additional distinctive phenotypic and functional features. Such adaptation of host NK cells to HCMV infection, confirmed in different clinical settings, is particularly magnified in immunocompromised patients and influenced by NKG2C gene copy number. The mechanism(s) underlying the differentiation and proliferation of NKG2C+ NK cells, the basis for the individual differences in the magnitude of their expansion, and their precise role in anti-viral defence remain open issues. Moreover, the possibility that the impact of HCMV infection on the NK-cell compartment may exert a broader influence on immunity deserves further attention." @default.
• W2040809972 created "2016-06-24" @default.
• W2040809972 creator A5018424217 @default.
• W2040809972 creator A5044514864 @default.
• W2040809972 creator A5044698710 @default.
• W2040809972 date "2014-04-01" @default.
• W2040809972 modified "2023-10-16" @default.
• W2040809972 title "The CD94/NKG2C+ NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection" @default.
• W2040809972 cites W1533264279 @default.
• W2040809972 cites W1585131641 @default.
• W2040809972 cites W1757602653 @default.
• W2040809972 cites W1928377279 @default.
• W2040809972 cites W1938553683 @default.
• W2040809972 cites W1966280572 @default.
• W2040809972 cites W1967920980 @default.
• W2040809972 cites W1969950463 @default.
• W2040809972 cites W1973646541 @default.
• W2040809972 cites W1980311294 @default.
• W2040809972 cites W1982084822 @default.
• W2040809972 cites W1983064582 @default.
• W2040809972 cites W1986696487 @default.
• W2040809972 cites W1991464577 @default.
• W2040809972 cites W1991689864 @default.
• W2040809972 cites W1992012316 @default.
• W2040809972 cites W1994255893 @default.
• W2040809972 cites W1996891899 @default.
• W2040809972 cites W2000115037 @default.
• W2040809972 cites W2000653963 @default.
• W2040809972 cites W2003676228 @default.
• W2040809972 cites W2003803349 @default.
• W2040809972 cites W2004205395 @default.
• W2040809972 cites W2007542983 @default.
• W2040809972 cites W2007851855 @default.
• W2040809972 cites W2008919922 @default.
• W2040809972 cites W2011017810 @default.
• W2040809972 cites W2011152725 @default.
• W2040809972 cites W2013784383 @default.
• W2040809972 cites W2014499991 @default.
• W2040809972 cites W2015863483 @default.
• W2040809972 cites W2019329212 @default.
• W2040809972 cites W2020929354 @default.
• W2040809972 cites W2022956462 @default.
• W2040809972 cites W2024579897 @default.
• W2040809972 cites W2027266738 @default.
• W2040809972 cites W2032715845 @default.
• W2040809972 cites W2035860688 @default.
• W2040809972 cites W2043570079 @default.
• W2040809972 cites W2051103323 @default.
• W2040809972 cites W2051890542 @default.
• W2040809972 cites W2052667644 @default.
• W2040809972 cites W2054150065 @default.
• W2040809972 cites W2059320400 @default.
• W2040809972 cites W2061630978 @default.
• W2040809972 cites W2062840842 @default.
• W2040809972 cites W2063317473 @default.
• W2040809972 cites W2064890413 @default.
• W2040809972 cites W2066082105 @default.
• W2040809972 cites W2074280192 @default.
• W2040809972 cites W2075551199 @default.
• W2040809972 cites W2076329388 @default.
• W2040809972 cites W2083592738 @default.
• W2040809972 cites W2084278750 @default.
• W2040809972 cites W2086230343 @default.
• W2040809972 cites W2090563229 @default.
• W2040809972 cites W2096119021 @default.
• W2040809972 cites W2098379604 @default.
• W2040809972 cites W2103365363 @default.
• W2040809972 cites W2108849105 @default.
• W2040809972 cites W2110942856 @default.
• W2040809972 cites W2115684094 @default.
• W2040809972 cites W2117282373 @default.
• W2040809972 cites W2122745552 @default.
• W2040809972 cites W2124235308 @default.
• W2040809972 cites W2124642065 @default.
• W2040809972 cites W2125163646 @default.
• W2040809972 cites W2130649175 @default.
• W2040809972 cites W2130963375 @default.
• W2040809972 cites W2132268212 @default.
• W2040809972 cites W2133272126 @default.
• W2040809972 cites W2135134003 @default.
• W2040809972 cites W2136558573 @default.
• W2040809972 cites W2142261360 @default.
• W2040809972 cites W2145786937 @default.
• W2040809972 cites W2145912834 @default.
• W2040809972 cites W2146261880 @default.
• W2040809972 cites W2146313292 @default.
• W2040809972 cites W2146701364 @default.
• W2040809972 cites W2146783950 @default.
• W2040809972 cites W2149532296 @default.
• W2040809972 cites W2149677876 @default.
• W2040809972 cites W2151186939 @default.
• W2040809972 cites W2153814300 @default.
• W2040809972 cites W2155326193 @default.
• W2040809972 cites W2155690142 @default.
• W2040809972 cites W2157709400 @default.
• W2040809972 cites W2157861528 @default.
• W2040809972 cites W2159934585 @default.
• W2040809972 cites W2160092751 @default.

• next