FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040825089> ?p ?o ?g. }

• W2040825089 endingPage "182" @default.
• W2040825089 startingPage "177" @default.
• W2040825089 abstract "Nitric oxide synthase (NOS) inhibitors alleviate the adverse effects of nitric oxide (NO) overproduction that occurs during peritonitis, a clinical condition that is accompanied by arginine deficiency. However, the variations in the disease severity and the dosage, route, and period of NOS inhibitor administration are debatable. Therefore, we investigated the dose effects of chronically infused NOS inhibitor, NG-nitro-L-arginine methyl ester (L-NAME) on the anabolism, inflammatory responses, and arginine metabolism in parenterally fed rats with cecal puncture-induced subacute peritonitis. Male Wistar rats were divided into 4 groups and were administered total parenteral nutrition solutions with 0, 5 (low dose), 25 (medium dose), or 50 (high dose) mg·kg−1·d−1 of L-NAME for 7 d. Sham-operated rats administered total parenteral nutrition solution and normal healthy rats fed chow diet were also included. Our results showed that parenteral infusion significantly decreased body weight gain and plasma citrulline concentrations. In rats with subacute peritonitis, the parenteral infusion-induced increases in circulating white blood cells and NO were significantly decreased, whereas the decrease in serum albumin levels was significantly increased. Rats with subacute peritonitis that were administered chronic infusion of L-NAME had a significantly reduced nitrogen balance. In addition, rats administered the medium dose of L-NAME had significantly increased plasma arginine, ornithine, glutamate, and proline. In conclusion, chronic infusion of NOS inhibitors may not alter systemic NO homeostasis and inflammatory response but may facilitate the production of arginine-associated amino acids and nitrogen excretion in cases of subacute peritonitis." @default.
• W2040825089 created "2016-06-24" @default.
• W2040825089 creator A5020442809 @default.
• W2040825089 creator A5046343318 @default.
• W2040825089 creator A5046975884 @default.
• W2040825089 creator A5059217742 @default.
• W2040825089 date "2011-01-01" @default.
• W2040825089 modified "2023-10-16" @default.
• W2040825089 title "Dose Effects of Chronically Infused Nitric Oxide Synthase Inhibitor NG-Nitro-L-arginine Methyl Ester on Anabolic Response and Arginine Metabolism in Rats with Subacute Peritonitis" @default.
• W2040825089 cites W1493808470 @default.
• W2040825089 cites W1800755133 @default.
• W2040825089 cites W1932201793 @default.
• W2040825089 cites W1971292024 @default.
• W2040825089 cites W1973295341 @default.
• W2040825089 cites W1990347899 @default.
• W2040825089 cites W1990802251 @default.
• W2040825089 cites W1995131286 @default.
• W2040825089 cites W2015139804 @default.
• W2040825089 cites W2030644133 @default.
• W2040825089 cites W2039686004 @default.
• W2040825089 cites W2040814813 @default.
• W2040825089 cites W2046871000 @default.
• W2040825089 cites W2057437209 @default.
• W2040825089 cites W2059430552 @default.
• W2040825089 cites W2068375719 @default.
• W2040825089 cites W2070782834 @default.
• W2040825089 cites W2079021402 @default.
• W2040825089 cites W2081549549 @default.
• W2040825089 cites W2088119537 @default.
• W2040825089 cites W2089598030 @default.
• W2040825089 cites W2113693672 @default.
• W2040825089 cites W2128278362 @default.
• W2040825089 cites W2129057166 @default.
• W2040825089 cites W2134944524 @default.
• W2040825089 cites W2149266508 @default.
• W2040825089 cites W2159827287 @default.
• W2040825089 cites W2161363220 @default.
• W2040825089 cites W2162482307 @default.
• W2040825089 cites W2411656134 @default.
• W2040825089 doi "https://doi.org/10.1248/bpb.34.177" @default.
• W2040825089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21415524" @default.
• W2040825089 hasPublicationYear "2011" @default.
• W2040825089 type Work @default.
• W2040825089 sameAs 2040825089 @default.
• W2040825089 citedByCount "4" @default.
• W2040825089 countsByYear W20408250892012 @default.
• W2040825089 countsByYear W20408250892013 @default.
• W2040825089 countsByYear W20408250892016 @default.
• W2040825089 crossrefType "journal-article" @default.
• W2040825089 hasAuthorship W2040825089A5020442809 @default.
• W2040825089 hasAuthorship W2040825089A5046343318 @default.
• W2040825089 hasAuthorship W2040825089A5046975884 @default.
• W2040825089 hasAuthorship W2040825089A5059217742 @default.
• W2040825089 hasBestOaLocation W20408250891 @default.
• W2040825089 hasConcept C1008401 @default.
• W2040825089 hasConcept C126322002 @default.
• W2040825089 hasConcept C134018914 @default.
• W2040825089 hasConcept C185592680 @default.
• W2040825089 hasConcept C2777468819 @default.
• W2040825089 hasConcept C2777622882 @default.
• W2040825089 hasConcept C2779129087 @default.
• W2040825089 hasConcept C2780199535 @default.
• W2040825089 hasConcept C515207424 @default.
• W2040825089 hasConcept C519581460 @default.
• W2040825089 hasConcept C55493867 @default.
• W2040825089 hasConcept C71924100 @default.
• W2040825089 hasConcept C98274493 @default.
• W2040825089 hasConceptScore W2040825089C1008401 @default.
• W2040825089 hasConceptScore W2040825089C126322002 @default.
• W2040825089 hasConceptScore W2040825089C134018914 @default.
• W2040825089 hasConceptScore W2040825089C185592680 @default.
• W2040825089 hasConceptScore W2040825089C2777468819 @default.
• W2040825089 hasConceptScore W2040825089C2777622882 @default.
• W2040825089 hasConceptScore W2040825089C2779129087 @default.
• W2040825089 hasConceptScore W2040825089C2780199535 @default.
• W2040825089 hasConceptScore W2040825089C515207424 @default.
• W2040825089 hasConceptScore W2040825089C519581460 @default.
• W2040825089 hasConceptScore W2040825089C55493867 @default.
• W2040825089 hasConceptScore W2040825089C71924100 @default.
• W2040825089 hasConceptScore W2040825089C98274493 @default.
• W2040825089 hasIssue "2" @default.
• W2040825089 hasLocation W20408250891 @default.
• W2040825089 hasLocation W20408250892 @default.
• W2040825089 hasOpenAccess W2040825089 @default.
• W2040825089 hasPrimaryLocation W20408250891 @default.
• W2040825089 hasRelatedWork W2042748276 @default.
• W2040825089 hasRelatedWork W2047346085 @default.
• W2040825089 hasRelatedWork W2055574143 @default.
• W2040825089 hasRelatedWork W2080330601 @default.
• W2040825089 hasRelatedWork W2090957628 @default.
• W2040825089 hasRelatedWork W2093996623 @default.
• W2040825089 hasRelatedWork W2167008296 @default.
• W2040825089 hasRelatedWork W2949423999 @default.
• W2040825089 hasRelatedWork W2168702221 @default.
• W2040825089 hasRelatedWork W2188027336 @default.
• W2040825089 hasVolume "34" @default.
• W2040825089 isParatext "false" @default.
• W2040825089 isRetracted "false" @default.

• next