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• W2040826054 abstract "It is shown that the dual to the linear programming problem that arises in constraint-based models of metabolism can be given a thermodynamic interpretation in which the shadow prices are chemical potential analogues, and the objective is to minimize free energy consumption given a free energy drain corresponding to growth. The interpretation is distinct from conventional nonequilibrium thermodynamics, although it does satisfy a minimum entropy production principle. It can be used to motivate extensions of constraint-based modeling, for example, to microbial ecosystems." @default.
• W2040826054 created "2016-06-24" @default.
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• W2040826054 date "2007-09-07" @default.
• W2040826054 modified "2023-10-03" @default.
• W2040826054 title "Duality, Thermodynamics, and the Linear Programming Problem in Constraint-Based Models of Metabolism" @default.
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• W2040826054 doi "https://doi.org/10.1103/physrevlett.99.108101" @default.
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