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- W2040858072 abstract "Abstract The drugs colchicine and vinblastine inhibit the ingestion of red blood cells by schistosomules of Schistosoma mansoni grown in vitro . Inhibition of feeding was accompanied by a concomitant accumulation of granules within the cells comprising the esophageal gland. No granules were observed in the lumen of the digestive tract. In control animals, microtubules were observed in the tegument and subtegumental cells of the esophagus. Following colchicine or vinblastine treatment, microtubules disappeared from these sites; in the latter instance, vinblastine-induced crystals were observed in the esophageal gland. The inhibition of secretion by colchicine and vinblastine is consistent with the theory of microtubular-directed secretory activities." @default.
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- W2040858072 title "Schistosoma mansoni: Colchicine and vinblastine effects on schistosomule digestive tract development in vitro" @default.
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- W2040858072 doi "https://doi.org/10.1016/0014-4894(77)90021-2" @default.
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