Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040859993> ?p ?o ?g. }
- W2040859993 endingPage "201" @default.
- W2040859993 startingPage "193" @default.
- W2040859993 abstract "Subcellular localization of RNAs is a critical biological process for generation of cellular asymmetries for many cell types and a critical step in axis determination during the early development of animals. We have identified transcripts localized to the anterior and posterior of honeybee oocyte using laser capture microscopy and microarray analysis. Analysis of orthologous transcripts in Drosophila indicates that many do not show a conserved pattern of localization. By microinjecting fluorescently labeled honeybee transcripts into Drosophila egg chambers we show that these RNAs become localized in a similar manner to their localization in honeybee oocytes, indicating conservation of the localization machinery. Thus while the mechanisms for localizing RNA are conserved, the complement of localized RNAs are not. We propose that this complement of localized RNAs may change relatively rapidly through the loss or evolution of signal sequences detected by the conserved localization machinery, and show this has occurred in one transcript that is localized in a novel way in the honeybee. Our proposal, that the acquisition of novel RNA localization is relatively easy to evolve, has implications for the evolution of symmetry breaking mechanisms that trigger axis formation and development in animal embryos." @default.
- W2040859993 created "2016-06-24" @default.
- W2040859993 creator A5062067044 @default.
- W2040859993 creator A5089446569 @default.
- W2040859993 date "2013-03-01" @default.
- W2040859993 modified "2023-09-25" @default.
- W2040859993 title "RNA localization in the honeybee (Apis mellifera) oocyte reveals insights about the evolution of RNA localization mechanisms" @default.
- W2040859993 cites W1523403186 @default.
- W2040859993 cites W1563746447 @default.
- W2040859993 cites W1571632059 @default.
- W2040859993 cites W1964318658 @default.
- W2040859993 cites W1964822872 @default.
- W2040859993 cites W1970284326 @default.
- W2040859993 cites W1976416223 @default.
- W2040859993 cites W1976500290 @default.
- W2040859993 cites W1986692329 @default.
- W2040859993 cites W1990387854 @default.
- W2040859993 cites W1996403019 @default.
- W2040859993 cites W2003365838 @default.
- W2040859993 cites W2006747935 @default.
- W2040859993 cites W2009112566 @default.
- W2040859993 cites W2009135466 @default.
- W2040859993 cites W2018908345 @default.
- W2040859993 cites W2026976517 @default.
- W2040859993 cites W2028093081 @default.
- W2040859993 cites W2030692936 @default.
- W2040859993 cites W2031569719 @default.
- W2040859993 cites W2032130584 @default.
- W2040859993 cites W2033159578 @default.
- W2040859993 cites W2038443908 @default.
- W2040859993 cites W2040155449 @default.
- W2040859993 cites W2053490809 @default.
- W2040859993 cites W2058859872 @default.
- W2040859993 cites W2063254325 @default.
- W2040859993 cites W2067920704 @default.
- W2040859993 cites W2079560802 @default.
- W2040859993 cites W2082264194 @default.
- W2040859993 cites W2083721652 @default.
- W2040859993 cites W2084532782 @default.
- W2040859993 cites W2086211657 @default.
- W2040859993 cites W2086578720 @default.
- W2040859993 cites W2088170594 @default.
- W2040859993 cites W2089897307 @default.
- W2040859993 cites W2095097030 @default.
- W2040859993 cites W2096334238 @default.
- W2040859993 cites W2097617128 @default.
- W2040859993 cites W2106365390 @default.
- W2040859993 cites W2106836312 @default.
- W2040859993 cites W2114641811 @default.
- W2040859993 cites W2117613537 @default.
- W2040859993 cites W2118059471 @default.
- W2040859993 cites W2119028928 @default.
- W2040859993 cites W2120731735 @default.
- W2040859993 cites W2123145399 @default.
- W2040859993 cites W2124815061 @default.
- W2040859993 cites W2133465414 @default.
- W2040859993 cites W2134538788 @default.
- W2040859993 cites W2144614846 @default.
- W2040859993 cites W2152695624 @default.
- W2040859993 cites W2158217645 @default.
- W2040859993 cites W2163482144 @default.
- W2040859993 cites W2167096602 @default.
- W2040859993 cites W2167179274 @default.
- W2040859993 cites W2168059187 @default.
- W2040859993 cites W2168220452 @default.
- W2040859993 cites W319819633 @default.
- W2040859993 doi "https://doi.org/10.1016/j.ydbio.2013.01.001" @default.
- W2040859993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23313731" @default.
- W2040859993 hasPublicationYear "2013" @default.
- W2040859993 type Work @default.
- W2040859993 sameAs 2040859993 @default.
- W2040859993 citedByCount "5" @default.
- W2040859993 countsByYear W20408599932014 @default.
- W2040859993 countsByYear W20408599932017 @default.
- W2040859993 countsByYear W20408599932019 @default.
- W2040859993 crossrefType "journal-article" @default.
- W2040859993 hasAuthorship W2040859993A5062067044 @default.
- W2040859993 hasAuthorship W2040859993A5089446569 @default.
- W2040859993 hasBestOaLocation W20408599931 @default.
- W2040859993 hasConcept C104317684 @default.
- W2040859993 hasConcept C196843134 @default.
- W2040859993 hasConcept C199216141 @default.
- W2040859993 hasConcept C2776690073 @default.
- W2040859993 hasConcept C2776879804 @default.
- W2040859993 hasConcept C3017666073 @default.
- W2040859993 hasConcept C54355233 @default.
- W2040859993 hasConcept C62203573 @default.
- W2040859993 hasConcept C67705224 @default.
- W2040859993 hasConcept C70721500 @default.
- W2040859993 hasConcept C86803240 @default.
- W2040859993 hasConcept C95444343 @default.
- W2040859993 hasConceptScore W2040859993C104317684 @default.
- W2040859993 hasConceptScore W2040859993C196843134 @default.
- W2040859993 hasConceptScore W2040859993C199216141 @default.
- W2040859993 hasConceptScore W2040859993C2776690073 @default.
- W2040859993 hasConceptScore W2040859993C2776879804 @default.
- W2040859993 hasConceptScore W2040859993C3017666073 @default.
- W2040859993 hasConceptScore W2040859993C54355233 @default.