FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040867029> ?p ?o ?g. }

• W2040867029 endingPage "71" @default.
• W2040867029 startingPage "61" @default.
• W2040867029 abstract "In general non-human primates are highly susceptible to infections with Mycobacterium tuberculosis which therefore presents an explosive health threat to colonies. To screen for M. tuberculosis infections in non-human primates, the skin test is routinely used. However, the reliability of this test in primates is debatable. The aim of this study was to compare relatively easy in vitro diagnostic tests for TB with the skin test for detection of a tuberculosis (TB) infection. Two in vitro assays, a whole blood interferon-gamma (WB IFN-gamma) assay and in vitro stimulation of isolated lymphocytes (PBMC IFN-gamma) were evaluated during both experimental TB infections in macaques as well as during an outbreak of TB in a macaque quarantine facility. The WB IFN-gamma assay was also evaluated on healthy old and new world monkeys. Our results show that both in vitro assays detected TB infection in macaques. All experimentally infected animals showed TB-specific responses in both assays. In contrast, several TB animals were not diagnosed TB positive using the skin test. In addition, during the outbreak in the quarantine facility one animal was not detected using the routinely used skin test, but it showed strong positive responses in the WB assay. In conclusion, the in vitro assays are a valuable tool for screening non-human primates for TB infection, especially because the assays cause relatively less stress for the animals compared to the skin test and give reproducible and reliable results." @default.
• W2040867029 created "2016-06-24" @default.
• W2040867029 creator A5007565015 @default.
• W2040867029 creator A5011722549 @default.
• W2040867029 creator A5023875949 @default.
• W2040867029 creator A5025754154 @default.
• W2040867029 creator A5061911871 @default.
• W2040867029 creator A5075110092 @default.
• W2040867029 creator A5088612791 @default.
• W2040867029 creator A5090428914 @default.
• W2040867029 date "2004-07-01" @default.
• W2040867029 modified "2023-09-27" @default.
• W2040867029 title "TB diagnosis in non-human primates: comparison of two interferon-γ assays and the skin test for identification of Mycobacterium tuberculosis infection" @default.
• W2040867029 cites W1970570244 @default.
• W2040867029 cites W1972504405 @default.
• W2040867029 cites W2022286024 @default.
• W2040867029 cites W2030224320 @default.
• W2040867029 cites W2031266347 @default.
• W2040867029 cites W2038451468 @default.
• W2040867029 cites W2045995030 @default.
• W2040867029 cites W2067147999 @default.
• W2040867029 cites W2080275391 @default.
• W2040867029 cites W2082386765 @default.
• W2040867029 cites W2101735877 @default.
• W2040867029 cites W2118905950 @default.
• W2040867029 cites W2130087209 @default.
• W2040867029 cites W2130299324 @default.
• W2040867029 cites W2138058988 @default.
• W2040867029 cites W2153867815 @default.
• W2040867029 cites W2168222911 @default.
• W2040867029 cites W2168466885 @default.
• W2040867029 cites W2315757227 @default.
• W2040867029 cites W2411849688 @default.
• W2040867029 cites W4250913453 @default.
• W2040867029 doi "https://doi.org/10.1016/j.vetimm.2004.03.003" @default.
• W2040867029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15182996" @default.
• W2040867029 hasPublicationYear "2004" @default.
• W2040867029 type Work @default.
• W2040867029 sameAs 2040867029 @default.
• W2040867029 citedByCount "47" @default.
• W2040867029 countsByYear W20408670292012 @default.
• W2040867029 countsByYear W20408670292013 @default.
• W2040867029 countsByYear W20408670292014 @default.
• W2040867029 countsByYear W20408670292015 @default.
• W2040867029 countsByYear W20408670292016 @default.
• W2040867029 countsByYear W20408670292017 @default.
• W2040867029 countsByYear W20408670292018 @default.
• W2040867029 countsByYear W20408670292019 @default.
• W2040867029 countsByYear W20408670292020 @default.
• W2040867029 countsByYear W20408670292021 @default.
• W2040867029 countsByYear W20408670292022 @default.
• W2040867029 countsByYear W20408670292023 @default.
• W2040867029 crossrefType "journal-article" @default.
• W2040867029 hasAuthorship W2040867029A5007565015 @default.
• W2040867029 hasAuthorship W2040867029A5011722549 @default.
• W2040867029 hasAuthorship W2040867029A5023875949 @default.
• W2040867029 hasAuthorship W2040867029A5025754154 @default.
• W2040867029 hasAuthorship W2040867029A5061911871 @default.
• W2040867029 hasAuthorship W2040867029A5075110092 @default.
• W2040867029 hasAuthorship W2040867029A5088612791 @default.
• W2040867029 hasAuthorship W2040867029A5090428914 @default.
• W2040867029 hasConcept C116675565 @default.
• W2040867029 hasConcept C142724271 @default.
• W2040867029 hasConcept C151730666 @default.
• W2040867029 hasConcept C159047783 @default.
• W2040867029 hasConcept C202751555 @default.
• W2040867029 hasConcept C203014093 @default.
• W2040867029 hasConcept C2777975735 @default.
• W2040867029 hasConcept C2778690821 @default.
• W2040867029 hasConcept C2778950215 @default.
• W2040867029 hasConcept C2780841837 @default.
• W2040867029 hasConcept C2781069245 @default.
• W2040867029 hasConcept C55493867 @default.
• W2040867029 hasConcept C71924100 @default.
• W2040867029 hasConcept C86803240 @default.
• W2040867029 hasConceptScore W2040867029C116675565 @default.
• W2040867029 hasConceptScore W2040867029C142724271 @default.
• W2040867029 hasConceptScore W2040867029C151730666 @default.
• W2040867029 hasConceptScore W2040867029C159047783 @default.
• W2040867029 hasConceptScore W2040867029C202751555 @default.
• W2040867029 hasConceptScore W2040867029C203014093 @default.
• W2040867029 hasConceptScore W2040867029C2777975735 @default.
• W2040867029 hasConceptScore W2040867029C2778690821 @default.
• W2040867029 hasConceptScore W2040867029C2778950215 @default.
• W2040867029 hasConceptScore W2040867029C2780841837 @default.
• W2040867029 hasConceptScore W2040867029C2781069245 @default.
• W2040867029 hasConceptScore W2040867029C55493867 @default.
• W2040867029 hasConceptScore W2040867029C71924100 @default.
• W2040867029 hasConceptScore W2040867029C86803240 @default.
• W2040867029 hasIssue "1-2" @default.
• W2040867029 hasLocation W20408670291 @default.
• W2040867029 hasLocation W20408670292 @default.
• W2040867029 hasOpenAccess W2040867029 @default.
• W2040867029 hasPrimaryLocation W20408670291 @default.
• W2040867029 hasRelatedWork W2045346151 @default.
• W2040867029 hasRelatedWork W2126526196 @default.
• W2040867029 hasRelatedWork W2145720533 @default.
• W2040867029 hasRelatedWork W2349894740 @default.

• next