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- W2040871005 abstract "Background : Several authors reported that there was a close relationship between unbound bilirubin concentrations and abnormal results of auditory brainstem responses. Full-term infants with high-unbound bilirubin concentrations who were treated with human albumin were followed to evaluate their hearing abilities by using auditory brainstem responses. Methods : Fifty-eight infants (gestational age, 39.4 ± 1.4 weeks; birthweight, 3245 ± 435 g) with high unbound bilirubin concentrations (≥0.9 µg/dL) were treated with intensive phototherapy. Twenty infants (control group) received only phototherapy, while 38 others (albumin-treated group) were also given i.v. human albumin administration (1 g/kg bodyweight) during the first 2 h of phototherapy. The follow-up study of auditory brainstem responses was carried out at 6 and 12 months of age. Development quotient tests were carried out at 18 months of age. Results : Abnormalities of auditory brainstem response were detected in three infants in the albumin-treated group and six infants in the control group at 6 months. Two infants in the albumin-treated group and four infants in the control group had improved at 12 months. The results of the follow-up study at 18 months of age in the both groups were normal with development quotient >85. No patients with hearing disability and cerebral palsy were clinically detected at the age of 2 years. Conclusion : The results suggest that albumin priming might be effective for decreasing the rate of auditory brainstem response abnormalities at 6 months." @default.
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- W2040871005 date "2002-10-01" @default.
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- W2040871005 title "Follow-up study of auditory brainstem responses in infants with high unbound bilirubin levels treated with albumin infusion therapy" @default.
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- W2040871005 doi "https://doi.org/10.1046/j.1442-200x.2002.01612.x" @default.
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