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- W2040877037 abstract "Abstract 1. 1. Intracellular concentrations of putrescine, spermidine and spermine in Leishmania donovani were measured in (a) freshly isolated amastigotes, (b) cells permitted to transform for 6 hr and (c) transformed promastigotes. 2. 2. All three polyamines were found in freshly isolated amastigotes but spermine was not detected in promastigotes. 3. 3. Cells permitted to transform for 6 hr showed a drop in their spermine concentration although no visible cytodifferentiation had occurred by this time. 4. 4. Conversion of [ 14 C]ornithine to spermine was found in both amastigotes and 6 hr transformed cells but not in promastigotes; control preparations from uninfected spleen converted very small amounts of [ 14 C]ornithine to spermine. 5. 5. Putrescine levels in promastigotes increased more than 17-fold over that found in amastigotes. 6. 6. Ornithine decarboxylase activity was found in all stages. 7. 7. This is the first report of the presence of spermine in a hemoflagellate." @default.
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- W2040877037 date "1980-01-01" @default.
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- W2040877037 title "Polyamines in the hemoflagellate, Leishmania donovani: evidence for spermine in the amastigote stage" @default.
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- W2040877037 doi "https://doi.org/10.1016/0305-0491(80)90069-3" @default.
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