FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040883901> ?p ?o ?g. }

• W2040883901 endingPage "468" @default.
• W2040883901 startingPage "463" @default.
• W2040883901 abstract "Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a small secretory glycoprotein with multifunctional activity including anti-apoptosis and the inhibition of matrix metalloproteinase in invasive breast carcinomas. There have been contradictory results as to whether TIMP-1 is a poor or good prognostic factor in breast cancer patients. To address this controversy, we conducted a meta-analysis for the relationship between TIMP-1 levels and prognostic parameters in the breast cancer. The relevant published studies were pooled according to the defined selection criteria. The effect sizes of overall survival and prognostic parameters were calculated by a hazard ratio (HR) or an odds ratio (OR). HRs or ORs were combined using a random-effects model. Survival outcomes between high or elevated and low or normal serum TIMP-1 levels were compared by uni- and multivariate analyses involving 886 and 844 breast cancer patients, respectively. Patients with high or elevated serum TIMP-1 levels had unfavorable survival outcomes compared to patients with low or normal serum TIMP-1 levels in the uni- and multivariate analyses (HR, 1.7 and 2.4; p <0.001 and p = 0.033, respectively). However, no survival difference was evident in the data from tissue TIMP-1 levels by enzyme-linked immunosorbent assay and the expression of tissue TIMP-1 mRNA. The high or positive immunohistochemical expression of tissue TIMP-1 protein was not related to adjusted and unadjusted HRs, lymph node metastasis, and clinical stages. This meta-analysis indicates that serum TIMP-1 levels may be useful for predicting survival outcomes of invasive breast cancer patients." @default.
• W2040883901 created "2016-06-24" @default.
• W2040883901 creator A5001129813 @default.
• W2040883901 creator A5077546080 @default.
• W2040883901 creator A5085982516 @default.
• W2040883901 date "2011-08-01" @default.
• W2040883901 modified "2023-09-25" @default.
• W2040883901 title "Serum TIMP-1 Predicts Survival Outcomes of Invasive Breast Carcinoma Patients: A Meta-analysis" @default.
• W2040883901 cites W1491678226 @default.
• W2040883901 cites W1539993673 @default.
• W2040883901 cites W1560000192 @default.
• W2040883901 cites W1594521865 @default.
• W2040883901 cites W1973259157 @default.
• W2040883901 cites W1988813081 @default.
• W2040883901 cites W1993424211 @default.
• W2040883901 cites W1998847259 @default.
• W2040883901 cites W2002072986 @default.
• W2040883901 cites W2005477076 @default.
• W2040883901 cites W2012794174 @default.
• W2040883901 cites W2017599076 @default.
• W2040883901 cites W2037910534 @default.
• W2040883901 cites W2047861359 @default.
• W2040883901 cites W2056901325 @default.
• W2040883901 cites W2064015154 @default.
• W2040883901 cites W2071919220 @default.
• W2040883901 cites W2075642745 @default.
• W2040883901 cites W2081630720 @default.
• W2040883901 cites W2083143922 @default.
• W2040883901 cites W2092670120 @default.
• W2040883901 cites W2094193884 @default.
• W2040883901 cites W2101995865 @default.
• W2040883901 cites W2119050264 @default.
• W2040883901 cites W2139133938 @default.
• W2040883901 cites W2140406690 @default.
• W2040883901 cites W2148130479 @default.
• W2040883901 cites W2153321407 @default.
• W2040883901 cites W2159365419 @default.
• W2040883901 cites W2170122400 @default.
• W2040883901 cites W2171935083 @default.
• W2040883901 cites W2188721005 @default.
• W2040883901 cites W24535428 @default.
• W2040883901 cites W67975532 @default.
• W2040883901 doi "https://doi.org/10.1016/j.arcmed.2011.09.006" @default.
• W2040883901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21945575" @default.
• W2040883901 hasPublicationYear "2011" @default.
• W2040883901 type Work @default.
• W2040883901 sameAs 2040883901 @default.
• W2040883901 citedByCount "8" @default.
• W2040883901 countsByYear W20408839012012 @default.
• W2040883901 countsByYear W20408839012014 @default.
• W2040883901 countsByYear W20408839012016 @default.
• W2040883901 countsByYear W20408839012018 @default.
• W2040883901 countsByYear W20408839012021 @default.
• W2040883901 countsByYear W20408839012022 @default.
• W2040883901 crossrefType "journal-article" @default.
• W2040883901 hasAuthorship W2040883901A5001129813 @default.
• W2040883901 hasAuthorship W2040883901A5077546080 @default.
• W2040883901 hasAuthorship W2040883901A5085982516 @default.
• W2040883901 hasConcept C121608353 @default.
• W2040883901 hasConcept C126322002 @default.
• W2040883901 hasConcept C143998085 @default.
• W2040883901 hasConcept C156957248 @default.
• W2040883901 hasConcept C204232928 @default.
• W2040883901 hasConcept C207103383 @default.
• W2040883901 hasConcept C38180746 @default.
• W2040883901 hasConcept C44249647 @default.
• W2040883901 hasConcept C50382708 @default.
• W2040883901 hasConcept C530470458 @default.
• W2040883901 hasConcept C71924100 @default.
• W2040883901 hasConcept C95190672 @default.
• W2040883901 hasConceptScore W2040883901C121608353 @default.
• W2040883901 hasConceptScore W2040883901C126322002 @default.
• W2040883901 hasConceptScore W2040883901C143998085 @default.
• W2040883901 hasConceptScore W2040883901C156957248 @default.
• W2040883901 hasConceptScore W2040883901C204232928 @default.
• W2040883901 hasConceptScore W2040883901C207103383 @default.
• W2040883901 hasConceptScore W2040883901C38180746 @default.
• W2040883901 hasConceptScore W2040883901C44249647 @default.
• W2040883901 hasConceptScore W2040883901C50382708 @default.
• W2040883901 hasConceptScore W2040883901C530470458 @default.
• W2040883901 hasConceptScore W2040883901C71924100 @default.
• W2040883901 hasConceptScore W2040883901C95190672 @default.
• W2040883901 hasIssue "6" @default.
• W2040883901 hasLocation W20408839011 @default.
• W2040883901 hasLocation W20408839012 @default.
• W2040883901 hasOpenAccess W2040883901 @default.
• W2040883901 hasPrimaryLocation W20408839011 @default.
• W2040883901 hasRelatedWork W1900595920 @default.
• W2040883901 hasRelatedWork W2036739911 @default.
• W2040883901 hasRelatedWork W2082392604 @default.
• W2040883901 hasRelatedWork W2554003122 @default.
• W2040883901 hasRelatedWork W2889691785 @default.
• W2040883901 hasRelatedWork W2969537103 @default.
• W2040883901 hasRelatedWork W3154231528 @default.
• W2040883901 hasRelatedWork W3185003217 @default.
• W2040883901 hasRelatedWork W4206071870 @default.
• W2040883901 hasRelatedWork W4322771458 @default.
• W2040883901 hasVolume "42" @default.

• next