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- W2040935007 abstract "Insulin-induced hypoglycemic coma is rapidly and dramatically reversed by the intravenous administration of glucose. This old observation attests to the efficient transfer of this lipid-insoluble sugar across the plasma membranes of the brain endothelial cells that constitute the blood–brain barrier. Moreover, glucose readily moves across the cellular membranes of neurons and glia to sustain their metabolism. The mechanism of the rapid transfer of glucose from blood into cerebrospinal fluid1 and the brain2 has the features of carrier-facilitated diffusion, whereby the combination of glucose with a membrane carrier or transporter facilitates its transfer across the intervening membranes and its entry into . . ." @default.
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- W2040935007 date "1991-09-05" @default.
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- W2040935007 title "The Glucose-Transporter Protein and Glucopenic Brain Injury" @default.
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- W2040935007 doi "https://doi.org/10.1056/nejm199109053251011" @default.
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