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- W2040951937 abstract "Abstract A combined study of the labelling methods of two important glucose-derivatives i.e. [ 18 F]2-deoxy-2-fluoro- d -glucose ([ 18 F]2-FDG) and [ 18 F]3-deoxy-3-fluoro- d -glucose ([ 18 F]3-FDG) is described. Using [ 18 F]fluoride as reacting agent produced in a water target via the 18 O(p, n) 18 F and 16 O( 3 He, p) 18 F reaction, respectively, nucleophilic aliphatic substitution was performed at the corresponding precursors i.e. methyl-4-,6-O-benzylidene-2,3-O-cyclic-sulfato-β- d -mannopyranoside and 1,2:5,6-di-O-isopropylidene-3-O-trifluoromethanesulfonyl-α- d -allofuranose. After hydrolysis of the corresponding intermediate [ 18 F]2-FDG and [ 18 F]3-FDG were obtained as injectable solutions with yields of 22 and 40% (decay corrected), respectively." @default.
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- W2040951937 date "1986-01-01" @default.
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- W2040951937 title "Synthesis of [18F]2-deoxy-2-fluoro-d-glucose and [18F]3-deoxy-3-fluoro-d-glucose with [18F]fluoride from a water target" @default.
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- W2040951937 doi "https://doi.org/10.1016/0883-2889(86)90285-6" @default.
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