Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040953063> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2040953063 endingPage "324" @default.
- W2040953063 startingPage "321" @default.
- W2040953063 abstract "Various studies have shown the benefit of topical vitamin D(3) analogues in the treatment of mild to moderate plaque psoriasis.Assessment of the efficacy, tolerability and safety of tacalcitol ointment in the long-term treatment of chronic plaque psoriasis in daily dermatological practice.In this open, multicentre, clinical phase IV study with a pre/post comparison design, 157 patients with chronic plaque psoriasis were included. Patients showing chronic plaque psoriasis, covering 7-20% of their body area, were treated with tacalcitol ointment (4 microg/g, Curatoderm) once daily and were assessed at baseline and monthly during the 6-month treatment period. The efficacy parameter psoriasis area and severity index (PASI) and total body surface involvement were assessed at each visit. Laboratory parameters were assessed at the beginning and at the end of the study. Adverse events were recorded at each visit.The mean PASI score decreased by 67%, and a marked reduction in sum scores of erythema, infiltration and desquamation was detected. The body area affected declined by 33% from 13.3 to 8.8%. There were no changes in laboratory parameters, and no case of hypercalcaemia was observed. No serious adverse events occurred during the study period. The recorded local side-effects were usually transient and mainly mild.Tacalcitol ointment is safe, well tolerated and provides a further option for patients with psoriasis up to 20% body surface affected. Tacalcitol treatment can be recommended as effective therapy for long-term control of chronic plaque psoriasis in dermatological practice." @default.
- W2040953063 created "2016-06-24" @default.
- W2040953063 creator A5013777456 @default.
- W2040953063 creator A5025044161 @default.
- W2040953063 date "2002-01-01" @default.
- W2040953063 modified "2023-10-03" @default.
- W2040953063 title "Tacalcitol Ointment for Long-Term Control of Chronic Plaque Psoriasis in Dermatological Practice" @default.
- W2040953063 cites W1987384652 @default.
- W2040953063 cites W2015018707 @default.
- W2040953063 cites W2017725856 @default.
- W2040953063 cites W2025692360 @default.
- W2040953063 cites W2039623906 @default.
- W2040953063 cites W2049745435 @default.
- W2040953063 cites W2090517179 @default.
- W2040953063 cites W2117578627 @default.
- W2040953063 cites W2127041477 @default.
- W2040953063 cites W2140793010 @default.
- W2040953063 cites W2155113592 @default.
- W2040953063 cites W2397959613 @default.
- W2040953063 cites W2594774980 @default.
- W2040953063 cites W2520152430 @default.
- W2040953063 doi "https://doi.org/10.1159/000063376" @default.
- W2040953063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12077538" @default.
- W2040953063 hasPublicationYear "2002" @default.
- W2040953063 type Work @default.
- W2040953063 sameAs 2040953063 @default.
- W2040953063 citedByCount "21" @default.
- W2040953063 countsByYear W20409530632013 @default.
- W2040953063 countsByYear W20409530632014 @default.
- W2040953063 countsByYear W20409530632016 @default.
- W2040953063 countsByYear W20409530632021 @default.
- W2040953063 countsByYear W20409530632023 @default.
- W2040953063 crossrefType "journal-article" @default.
- W2040953063 hasAuthorship W2040953063A5013777456 @default.
- W2040953063 hasAuthorship W2040953063A5025044161 @default.
- W2040953063 hasConcept C126322002 @default.
- W2040953063 hasConcept C141071460 @default.
- W2040953063 hasConcept C16005928 @default.
- W2040953063 hasConcept C197934379 @default.
- W2040953063 hasConcept C2777011040 @default.
- W2040953063 hasConcept C2777501473 @default.
- W2040953063 hasConcept C2778375690 @default.
- W2040953063 hasConcept C2779121184 @default.
- W2040953063 hasConcept C2780564577 @default.
- W2040953063 hasConcept C3020604521 @default.
- W2040953063 hasConcept C71924100 @default.
- W2040953063 hasConceptScore W2040953063C126322002 @default.
- W2040953063 hasConceptScore W2040953063C141071460 @default.
- W2040953063 hasConceptScore W2040953063C16005928 @default.
- W2040953063 hasConceptScore W2040953063C197934379 @default.
- W2040953063 hasConceptScore W2040953063C2777011040 @default.
- W2040953063 hasConceptScore W2040953063C2777501473 @default.
- W2040953063 hasConceptScore W2040953063C2778375690 @default.
- W2040953063 hasConceptScore W2040953063C2779121184 @default.
- W2040953063 hasConceptScore W2040953063C2780564577 @default.
- W2040953063 hasConceptScore W2040953063C3020604521 @default.
- W2040953063 hasConceptScore W2040953063C71924100 @default.
- W2040953063 hasIssue "4" @default.
- W2040953063 hasLocation W20409530631 @default.
- W2040953063 hasLocation W20409530632 @default.
- W2040953063 hasOpenAccess W2040953063 @default.
- W2040953063 hasPrimaryLocation W20409530631 @default.
- W2040953063 hasRelatedWork W1485326008 @default.
- W2040953063 hasRelatedWork W1979916095 @default.
- W2040953063 hasRelatedWork W1989170203 @default.
- W2040953063 hasRelatedWork W2039876145 @default.
- W2040953063 hasRelatedWork W2040953063 @default.
- W2040953063 hasRelatedWork W2059983379 @default.
- W2040953063 hasRelatedWork W2362362345 @default.
- W2040953063 hasRelatedWork W2898213950 @default.
- W2040953063 hasRelatedWork W2944249074 @default.
- W2040953063 hasRelatedWork W4254680666 @default.
- W2040953063 hasVolume "204" @default.
- W2040953063 isParatext "false" @default.
- W2040953063 isRetracted "false" @default.
- W2040953063 magId "2040953063" @default.
- W2040953063 workType "article" @default.