FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040954358> ?p ?o ?g. }

• W2040954358 endingPage "4995" @default.
• W2040954358 startingPage "4986" @default.
• W2040954358 abstract "ABSTRACT Inulin is a well-known fructose-based prebiotic which has been shown to stimulate the growth of bifidobacteria, a bacterial group generally considered beneficial for intestinal health. In the present study, we analyzed inulin-associated shifts in the total bacterial community of wild-type mice and mice carrying a genetically inactivated adenomatous polyposis coli tumor suppressor gene by using DNA-based approaches independent of bacterial culturability. Mice were fed a high-fat, nonfiber diet with or without inulin inclusion at a 10% (wt/wt) concentration. Cecal contents were analyzed after 0, 3, and 9 weeks on the experimental diets. Inulin inclusion significantly affected the total bacterial community structure of the cecum as determined by both a nonselective percent-guanine-plus-cytosine-based profiling analysis and a more specific 16S ribosomal DNA sequence analysis. The shifts included stimulation of bifidobacteria and suppression of clostridia, but sequence comparison revealed that the major shifts were within previously unknown bacterial taxa. Concomitantly, significantly higher bacterial densities, determined by flow cytometry, were observed with the inulin-amended diet, and the metabolism of the cecal bacterial community was altered, as indicated by higher levels of residual short-chain fatty acids, particularly lactic acid. With regard to all of the microbiological parameters measured, the wild-type mice and mice carrying a genetically inactivated adenomatous polyposis coli tumor suppressor gene were essentially identical. Studies of the implications of pre- and probiotics may need to be expanded to include careful analysis of their effects on the entire microbial community, rather than just a few well-known species. Further studies are needed to increase our understanding of the possible roles of currently unknown gastrointestinal bacteria in health and disease." @default.
• W2040954358 created "2016-06-24" @default.
• W2040954358 creator A5005045340 @default.
• W2040954358 creator A5021725332 @default.
• W2040954358 creator A5038277084 @default.
• W2040954358 creator A5050719384 @default.
• W2040954358 creator A5057348487 @default.
• W2040954358 creator A5077944041 @default.
• W2040954358 creator A5090943466 @default.
• W2040954358 date "2002-10-01" @default.
• W2040954358 modified "2023-10-14" @default.
• W2040954358 title "Culture-Independent Microbial Community Analysis Reveals that Inulin in the Diet Primarily Affects Previously Unknown Bacteria in the Mouse Cecum" @default.
• W2040954358 cites W1533296893 @default.
• W2040954358 cites W1831301545 @default.
• W2040954358 cites W1867313808 @default.
• W2040954358 cites W1966919146 @default.
• W2040954358 cites W1986398106 @default.
• W2040954358 cites W1996057585 @default.
• W2040954358 cites W1998103368 @default.
• W2040954358 cites W1999128996 @default.
• W2040954358 cites W2001862498 @default.
• W2040954358 cites W2019331670 @default.
• W2040954358 cites W2036059068 @default.
• W2040954358 cites W2038074929 @default.
• W2040954358 cites W2048509314 @default.
• W2040954358 cites W2082008751 @default.
• W2040954358 cites W2090037571 @default.
• W2040954358 cites W2090378784 @default.
• W2040954358 cites W2100415121 @default.
• W2040954358 cites W2103279956 @default.
• W2040954358 cites W2105046957 @default.
• W2040954358 cites W2106253081 @default.
• W2040954358 cites W2112209281 @default.
• W2040954358 cites W2120643571 @default.
• W2040954358 cites W2121590623 @default.
• W2040954358 cites W2131361193 @default.
• W2040954358 cites W2131988453 @default.
• W2040954358 cites W2139890082 @default.
• W2040954358 cites W2140183033 @default.
• W2040954358 cites W2146448202 @default.
• W2040954358 cites W2146565796 @default.
• W2040954358 cites W2154299618 @default.
• W2040954358 cites W2157872440 @default.
• W2040954358 cites W2161247570 @default.
• W2040954358 cites W2161532729 @default.
• W2040954358 cites W2161589983 @default.
• W2040954358 cites W2167497377 @default.
• W2040954358 cites W2168522001 @default.
• W2040954358 cites W2170360177 @default.
• W2040954358 cites W2220516585 @default.
• W2040954358 cites W2317360080 @default.
• W2040954358 cites W2455302 @default.
• W2040954358 cites W4241328656 @default.
• W2040954358 doi "https://doi.org/10.1128/aem.68.10.4986-4995.2002" @default.
• W2040954358 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/126397" @default.
• W2040954358 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12324348" @default.
• W2040954358 hasPublicationYear "2002" @default.
• W2040954358 type Work @default.
• W2040954358 sameAs 2040954358 @default.
• W2040954358 citedByCount "126" @default.
• W2040954358 countsByYear W20409543582012 @default.
• W2040954358 countsByYear W20409543582013 @default.
• W2040954358 countsByYear W20409543582014 @default.
• W2040954358 countsByYear W20409543582015 @default.
• W2040954358 countsByYear W20409543582016 @default.
• W2040954358 countsByYear W20409543582017 @default.
• W2040954358 countsByYear W20409543582018 @default.
• W2040954358 countsByYear W20409543582019 @default.
• W2040954358 countsByYear W20409543582020 @default.
• W2040954358 countsByYear W20409543582021 @default.
• W2040954358 countsByYear W20409543582022 @default.
• W2040954358 countsByYear W20409543582023 @default.
• W2040954358 crossrefType "journal-article" @default.
• W2040954358 hasAuthorship W2040954358A5005045340 @default.
• W2040954358 hasAuthorship W2040954358A5021725332 @default.
• W2040954358 hasAuthorship W2040954358A5038277084 @default.
• W2040954358 hasAuthorship W2040954358A5050719384 @default.
• W2040954358 hasAuthorship W2040954358A5057348487 @default.
• W2040954358 hasAuthorship W2040954358A5077944041 @default.
• W2040954358 hasAuthorship W2040954358A5090943466 @default.
• W2040954358 hasBestOaLocation W20409543582 @default.
• W2040954358 hasConcept C100544194 @default.
• W2040954358 hasConcept C143121216 @default.
• W2040954358 hasConcept C18903297 @default.
• W2040954358 hasConcept C2775980262 @default.
• W2040954358 hasConcept C2776229602 @default.
• W2040954358 hasConcept C2776970464 @default.
• W2040954358 hasConcept C2776979534 @default.
• W2040954358 hasConcept C2777507495 @default.
• W2040954358 hasConcept C2779742124 @default.
• W2040954358 hasConcept C31903555 @default.
• W2040954358 hasConcept C523546767 @default.
• W2040954358 hasConcept C54355233 @default.
• W2040954358 hasConcept C86803240 @default.
• W2040954358 hasConcept C89423630 @default.
• W2040954358 hasConceptScore W2040954358C100544194 @default.
• W2040954358 hasConceptScore W2040954358C143121216 @default.
• W2040954358 hasConceptScore W2040954358C18903297 @default.

• next