Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040963896> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2040963896 endingPage "304" @default.
- W2040963896 startingPage "298" @default.
- W2040963896 abstract "An explanation for the origin and the high concentration of vitamin D (cholecalciferol) in some species of fish is still not apparent. Because fish may live in deep water and may, thus, not be exposed to solar ultraviolet (UV) light, it is commonly assumed that vitamin D found in their livers and adipose tissue has been derived from a food chain, originating in zooplankton exposed to UV light at the water surface. To investigate the metabolism and possible origin of vitamin D in fish, rainbow trout were reared from eggs, in the absence of light, and were fed a vitamin D-free diet. When small quantities of radioactively-labelled vitamin D were injected or fed to these trout, much of the radioactivity was found as excreted metabolites in bile. Hence, even when they are vitamin D deficient, trout vigorously catabolise and excrete exogenous vitamin D. The main vitamin D metabolite found in plasma of non-deficient trout was 1,25-dihydroxycholecalciferol [1,25(OH)2D3]. This was produced in the liver by an enzyme process that was strongly stimulated in vitamin D deficiency. When vitamin D was fed for several weeks to vitamin D-deficient trout, plasma 1,25(OH)2D3 levels rose to 180 pg/ml and the fish became hypercalcemic. When vitamin D-deficient fish were inadvertently exposed to 60 W incandescent light for 24 h, they became moribund and died. It was subsequently found that vitamin D-deficient trout can produce vitamin D in skin when exposed to blue light at wavelengths between 380 and 480 nm. It is concluded that trout, like terrestrial vertebrates, produce 1,25(OH)2D3 as the functional form of vitamin D and that this has an effect on calcium homeostasis. Furthermore, vitamin D is formed in the skin of these fish by the photochemical action of visible light on 7-dehydrocholesterol. Elucidation of the physicochemical mechanism of this process requires further research." @default.
- W2040963896 created "2016-06-24" @default.
- W2040963896 creator A5031423888 @default.
- W2040963896 creator A5034716899 @default.
- W2040963896 date "2015-04-01" @default.
- W2040963896 modified "2023-09-26" @default.
- W2040963896 title "Reprint of “The origin and metabolism of vitamin D in rainbow trout”" @default.
- W2040963896 cites W1206058226 @default.
- W2040963896 cites W1601742234 @default.
- W2040963896 cites W1989996614 @default.
- W2040963896 cites W2002550598 @default.
- W2040963896 cites W2003065493 @default.
- W2040963896 cites W2007978910 @default.
- W2040963896 cites W2026850533 @default.
- W2040963896 cites W2035080939 @default.
- W2040963896 cites W2038614023 @default.
- W2040963896 cites W2041175719 @default.
- W2040963896 cites W2044240836 @default.
- W2040963896 cites W2053615324 @default.
- W2040963896 cites W2060493036 @default.
- W2040963896 cites W2065851383 @default.
- W2040963896 cites W2123812398 @default.
- W2040963896 cites W2154372139 @default.
- W2040963896 cites W2159450232 @default.
- W2040963896 cites W2223337526 @default.
- W2040963896 cites W2237783202 @default.
- W2040963896 cites W2297808785 @default.
- W2040963896 cites W2315566694 @default.
- W2040963896 cites W2331022556 @default.
- W2040963896 cites W2415577285 @default.
- W2040963896 doi "https://doi.org/10.1016/j.jsbmb.2015.01.025" @default.
- W2040963896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25644203" @default.
- W2040963896 hasPublicationYear "2015" @default.
- W2040963896 type Work @default.
- W2040963896 sameAs 2040963896 @default.
- W2040963896 citedByCount "2" @default.
- W2040963896 countsByYear W20409638962018 @default.
- W2040963896 countsByYear W20409638962020 @default.
- W2040963896 crossrefType "journal-article" @default.
- W2040963896 hasAuthorship W2040963896A5031423888 @default.
- W2040963896 hasAuthorship W2040963896A5034716899 @default.
- W2040963896 hasConcept C121332964 @default.
- W2040963896 hasConcept C124490489 @default.
- W2040963896 hasConcept C126322002 @default.
- W2040963896 hasConcept C1276947 @default.
- W2040963896 hasConcept C134018914 @default.
- W2040963896 hasConcept C170853661 @default.
- W2040963896 hasConcept C185592680 @default.
- W2040963896 hasConcept C2776940978 @default.
- W2040963896 hasConcept C2777940460 @default.
- W2040963896 hasConcept C2779363728 @default.
- W2040963896 hasConcept C2780106736 @default.
- W2040963896 hasConcept C2909208804 @default.
- W2040963896 hasConcept C2987116853 @default.
- W2040963896 hasConcept C2994167347 @default.
- W2040963896 hasConcept C505870484 @default.
- W2040963896 hasConcept C62231903 @default.
- W2040963896 hasConcept C71924100 @default.
- W2040963896 hasConcept C75473681 @default.
- W2040963896 hasConcept C86803240 @default.
- W2040963896 hasConceptScore W2040963896C121332964 @default.
- W2040963896 hasConceptScore W2040963896C124490489 @default.
- W2040963896 hasConceptScore W2040963896C126322002 @default.
- W2040963896 hasConceptScore W2040963896C1276947 @default.
- W2040963896 hasConceptScore W2040963896C134018914 @default.
- W2040963896 hasConceptScore W2040963896C170853661 @default.
- W2040963896 hasConceptScore W2040963896C185592680 @default.
- W2040963896 hasConceptScore W2040963896C2776940978 @default.
- W2040963896 hasConceptScore W2040963896C2777940460 @default.
- W2040963896 hasConceptScore W2040963896C2779363728 @default.
- W2040963896 hasConceptScore W2040963896C2780106736 @default.
- W2040963896 hasConceptScore W2040963896C2909208804 @default.
- W2040963896 hasConceptScore W2040963896C2987116853 @default.
- W2040963896 hasConceptScore W2040963896C2994167347 @default.
- W2040963896 hasConceptScore W2040963896C505870484 @default.
- W2040963896 hasConceptScore W2040963896C62231903 @default.
- W2040963896 hasConceptScore W2040963896C71924100 @default.
- W2040963896 hasConceptScore W2040963896C75473681 @default.
- W2040963896 hasConceptScore W2040963896C86803240 @default.
- W2040963896 hasLocation W20409638961 @default.
- W2040963896 hasLocation W20409638962 @default.
- W2040963896 hasOpenAccess W2040963896 @default.
- W2040963896 hasPrimaryLocation W20409638961 @default.
- W2040963896 hasRelatedWork W1971878843 @default.
- W2040963896 hasRelatedWork W2017131741 @default.
- W2040963896 hasRelatedWork W2066417673 @default.
- W2040963896 hasRelatedWork W2167936431 @default.
- W2040963896 hasRelatedWork W2314615196 @default.
- W2040963896 hasRelatedWork W2323176791 @default.
- W2040963896 hasRelatedWork W2338559300 @default.
- W2040963896 hasRelatedWork W3148998968 @default.
- W2040963896 hasRelatedWork W828079486 @default.
- W2040963896 hasRelatedWork W2185339440 @default.
- W2040963896 hasVolume "148" @default.
- W2040963896 isParatext "false" @default.
- W2040963896 isRetracted "false" @default.
- W2040963896 magId "2040963896" @default.
- W2040963896 workType "article" @default.