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- W2040984967 abstract "In this study, plasma and platelet taurine content and fluxes were determined in 38 type 2 diabetic patients and in 26 healthy control subjects. Taurine levels in diabetic patients were significantly lower than in control subjects both in plasma (32.1 v 48.6 micromol/L, P = .000) and platelets (148 v 183 nmol/mg protein, P = .043). Platelet taurine uptake in diabetic patients was significantly reduced (321.2 v 524.9 pmol total taurine 10(8) platelet(-1) min(-20), P = .000), whereas taurine release increased in comparison to healthy controls (38.7 v 29.5% of platelet 3H taurine at the start of incubation, P = .000). These results may reflect modified systems of taurine carriers or a compensatory mechanism in response to an increase of other organic osmolytes." @default.
- W2040984967 created "2016-06-24" @default.
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- W2040984967 date "2001-01-01" @default.
- W2040984967 modified "2023-10-09" @default.
- W2040984967 title "Taurine and osmoregulation: Platelet taurine content, uptake, and release in type 2 diabetic patients" @default.
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- W2040984967 doi "https://doi.org/10.1053/meta.2001.19432" @default.
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