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- W2040989827 abstract "Prediction of physical appearance based on genetic analysis is a very attractive prospect for forensic investigations. Recent studies have proved that there is a significant association between some genetic variants of the melanocortin 1 receptor (MC1R) gene and red hair color. The present study focuses on the potential forensic applicability of variation within this pigment-related gene. Sequencing of the complete MC1R gene was performed on a group of red-haired individuals and controls with different pigmentation. A major role in determination of red hair color is played by two MC1R variants--C451T and C478T. The optimized minisequencing assay for genotyping of the above positions and three other important red hair-related MC1R polymorphisms, C252A, G425A, and G880C was successfully applied to analyze typical forensic specimens. Determination of a homozygous or heterozygous combination can be a good predictor of both red hair color and fair skin of a subject." @default.
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- W2040989827 date "2007-03-01" @default.
- W2040989827 modified "2023-10-18" @default.
- W2040989827 title "Determination of Phenotype Associated SNPs in the MC1R Gene" @default.
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- W2040989827 doi "https://doi.org/10.1111/j.1556-4029.2006.00361.x" @default.
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