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- W2040994049 abstract "Whereas beta-2-microglobulin (beta2M) has mainly been used as a prognostic factor in patients with lymphoproliferative disorders, some studies have reported the value of beta2M in myeloproliferative disorders (MPD). In order to investigate a potential role in the pathogenesis of MPD and to find a possible value as indicators in monitoring the course of the disease, we measured beta2M, TNF-alpha, IL-1alpha, IL-1beta, IL-2, sIL-2R, IL-6 and IL-10 in 55 patients with MPD, at diagnosis and during the course of the disease. In progressive disease and particularly when transformation to acute leukemia occurred, high levels of beta2M, IL-2 and sIL-2R were found in all patients; the elevation was progressive, which suggests a potential prognostic usefulness in the individual patient." @default.
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- W2040994049 date "2009-04-24" @default.
- W2040994049 modified "2023-10-06" @default.
- W2040994049 title "Serum beta-2-microglobulin, TNF-α and interleukins in myeloproliferative disorders" @default.
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- W2040994049 doi "https://doi.org/10.1111/j.1600-0609.1999.tb01845.x" @default.
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