FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040994140> ?p ?o ?g. }

• W2040994140 endingPage "402" @default.
• W2040994140 startingPage "393" @default.
• W2040994140 abstract "This study aimed to determine the skeletal effects of total ethanolic extract (TEE) and its butanolic fraction (BF) from the stem-bark of Ulmus wallichiana, which is rich in C-glycosylated flavonoids, in growing rats (for peak bone [PB] achievement) and in ovariectomized (OVx) rats (for menopausal bone loss).TEE (750 mg kg(-1) d(-1)) and BF (50 mg kg(-1) d(-1)) were given orally for 10 weeks to weaning female Sprague-Dawley rats and for 12 weeks to adult OVx rats of the same strain, respectively. In studies with OVx rats, sham operated + vehicle, OVx + 17beta-estradiol, and OVx + vehicle groups served as various controls. Bone mineral density (BMD), biomechanical strength, bone histology, formations of osteoprogenitor cells, osteoid formation, and bone turnover/resorption markers were studied. Bioactive marker compounds in TEE and BF were analyzed by high-performance liquid chromatography. One-way analysis of variance was used to test significance of effects.In growing rats, both TEE and BF increased BMD, bone strength, and bone formation rate, suggesting higher PB achievement. OVx rats treated with either TEE or BF exhibited increased BMD at various anatomical positions and improved bone strength and trabecular architecture compared with the OVx + vehicle group. Serum osteocalcin and urinary type 1 collagen degradation product levels in OVx rats treated with either TEE or BF were significantly lower than those of the OVx + vehicle group. Neither TEE nor BF exhibited uterine estrogenicity. Analysis of marker compounds revealed significant enrichment of two bioactive markers in BF over TEE.Derived from U wallichiana, BF at much a lower dose than TEE was effective in PB achievement and prevention of OVx-induced bone loss." @default.
• W2040994140 created "2016-06-24" @default.
• W2040994140 creator A5020267991 @default.
• W2040994140 creator A5020426573 @default.
• W2040994140 creator A5025690580 @default.
• W2040994140 creator A5029955399 @default.
• W2040994140 creator A5036594335 @default.
• W2040994140 creator A5038669110 @default.
• W2040994140 creator A5061891654 @default.
• W2040994140 creator A5065166301 @default.
• W2040994140 creator A5066141947 @default.
• W2040994140 creator A5069222648 @default.
• W2040994140 creator A5075751912 @default.
• W2040994140 creator A5081244725 @default.
• W2040994140 creator A5082476907 @default.
• W2040994140 date "2010-03-01" @default.
• W2040994140 modified "2023-09-23" @default.
• W2040994140 title "Extract and fraction from Ulmus wallichiana Planchon promote peak bone achievement and have a nonestrogenic osteoprotective effect" @default.
• W2040994140 cites W1965062393 @default.
• W2040994140 cites W1965565026 @default.
• W2040994140 cites W1986276800 @default.
• W2040994140 cites W1989530871 @default.
• W2040994140 cites W1991540139 @default.
• W2040994140 cites W2019323686 @default.
• W2040994140 cites W2027093084 @default.
• W2040994140 cites W2029697567 @default.
• W2040994140 cites W2038534576 @default.
• W2040994140 cites W2060662815 @default.
• W2040994140 cites W2062254932 @default.
• W2040994140 cites W2080147361 @default.
• W2040994140 cites W2085597991 @default.
• W2040994140 cites W2098868165 @default.
• W2040994140 cites W2100249043 @default.
• W2040994140 cites W2121836743 @default.
• W2040994140 cites W2157121861 @default.
• W2040994140 cites W2158389289 @default.
• W2040994140 doi "https://doi.org/10.1097/gme.0b013e3181bfae38" @default.
• W2040994140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20009959" @default.
• W2040994140 hasPublicationYear "2010" @default.
• W2040994140 type Work @default.
• W2040994140 sameAs 2040994140 @default.
• W2040994140 citedByCount "29" @default.
• W2040994140 countsByYear W20409941402012 @default.
• W2040994140 countsByYear W20409941402013 @default.
• W2040994140 countsByYear W20409941402014 @default.
• W2040994140 countsByYear W20409941402015 @default.
• W2040994140 countsByYear W20409941402016 @default.
• W2040994140 countsByYear W20409941402018 @default.
• W2040994140 countsByYear W20409941402020 @default.
• W2040994140 countsByYear W20409941402023 @default.
• W2040994140 crossrefType "journal-article" @default.
• W2040994140 hasAuthorship W2040994140A5020267991 @default.
• W2040994140 hasAuthorship W2040994140A5020426573 @default.
• W2040994140 hasAuthorship W2040994140A5025690580 @default.
• W2040994140 hasAuthorship W2040994140A5029955399 @default.
• W2040994140 hasAuthorship W2040994140A5036594335 @default.
• W2040994140 hasAuthorship W2040994140A5038669110 @default.
• W2040994140 hasAuthorship W2040994140A5061891654 @default.
• W2040994140 hasAuthorship W2040994140A5065166301 @default.
• W2040994140 hasAuthorship W2040994140A5066141947 @default.
• W2040994140 hasAuthorship W2040994140A5069222648 @default.
• W2040994140 hasAuthorship W2040994140A5075751912 @default.
• W2040994140 hasAuthorship W2040994140A5081244725 @default.
• W2040994140 hasAuthorship W2040994140A5082476907 @default.
• W2040994140 hasConcept C126322002 @default.
• W2040994140 hasConcept C131075544 @default.
• W2040994140 hasConcept C134018914 @default.
• W2040994140 hasConcept C160160445 @default.
• W2040994140 hasConcept C170033053 @default.
• W2040994140 hasConcept C181199279 @default.
• W2040994140 hasConcept C185592680 @default.
• W2040994140 hasConcept C2776541429 @default.
• W2040994140 hasConcept C2776886416 @default.
• W2040994140 hasConcept C2777164284 @default.
• W2040994140 hasConcept C2780787237 @default.
• W2040994140 hasConcept C55493867 @default.
• W2040994140 hasConcept C673006 @default.
• W2040994140 hasConcept C71924100 @default.
• W2040994140 hasConcept C8264082 @default.
• W2040994140 hasConceptScore W2040994140C126322002 @default.
• W2040994140 hasConceptScore W2040994140C131075544 @default.
• W2040994140 hasConceptScore W2040994140C134018914 @default.
• W2040994140 hasConceptScore W2040994140C160160445 @default.
• W2040994140 hasConceptScore W2040994140C170033053 @default.
• W2040994140 hasConceptScore W2040994140C181199279 @default.
• W2040994140 hasConceptScore W2040994140C185592680 @default.
• W2040994140 hasConceptScore W2040994140C2776541429 @default.
• W2040994140 hasConceptScore W2040994140C2776886416 @default.
• W2040994140 hasConceptScore W2040994140C2777164284 @default.
• W2040994140 hasConceptScore W2040994140C2780787237 @default.
• W2040994140 hasConceptScore W2040994140C55493867 @default.
• W2040994140 hasConceptScore W2040994140C673006 @default.
• W2040994140 hasConceptScore W2040994140C71924100 @default.
• W2040994140 hasConceptScore W2040994140C8264082 @default.
• W2040994140 hasIssue "2" @default.
• W2040994140 hasLocation W20409941401 @default.
• W2040994140 hasLocation W20409941402 @default.
• W2040994140 hasOpenAccess W2040994140 @default.

• next