FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040994702> ?p ?o ?g. }

• W2040994702 endingPage "469" @default.
• W2040994702 startingPage "465" @default.
• W2040994702 abstract "Human macroaggregated albumin (MAA), which is currently labeled with technetium-99m (99mTc) and 99mTc-MAA, is used clinically as a pulmonary perfusion agent and was directly labeled with yttrium-90 (90Y)-acetate. This study evaluated whether 90Y-MAA could be potential radiotherapeutic agent for regional radiotherapy against malignant tumors. MAA suspended in 0.1 M sodium acetate buffer, pH 5.8, was incubated with 90Y-acetate and purified in order to get rid of unstable binding of 90Y by electrophoresis. The radiochemical purity of 90Y-MAA in normal human serum was estimated by an agarose electrophoresis method and was more than 94% over 168 h in vitro. Following the intratumoral administration of 90Y-MAA, the time course of tumor radioactivity and the biodistribution in nude mice bearing human neuroblastoma were investigated up to 168 h. More than 93% of the radioactivity of the injected dose was found on the subcutaneous tumor over 168 h. The bone radioactivity was shown as 0.06 +/- 0.03% injection dose/gram tissue (% ID/g) (n = 5) at 24 h, 0.73 +/- 0.20% ID/g at 72 h, 0.92 +/- 0.16% ID/g at 120 h, and 2.51 +/- 0.59% ID/g at 168 h. A slight increase in radioactivity was noted in the liver, kidneys, and spleen over the 168-h periods. In conclusion, 90Y-MAA may be a potential agent for regional radiotherapy (brachytherapy) because of the sufficient persistence in the tumor following an intratumoral administration." @default.
• W2040994702 created "2016-06-24" @default.
• W2040994702 creator A5009855950 @default.
• W2040994702 creator A5010422674 @default.
• W2040994702 creator A5012921572 @default.
• W2040994702 creator A5023225044 @default.
• W2040994702 creator A5026011582 @default.
• W2040994702 creator A5034452868 @default.
• W2040994702 creator A5044873442 @default.
• W2040994702 creator A5054069029 @default.
• W2040994702 creator A5083301071 @default.
• W2040994702 creator A5083595584 @default.
• W2040994702 date "1997-07-01" @default.
• W2040994702 modified "2023-09-23" @default.
• W2040994702 title "Preparation of yttrium-90-labeled human macroaggregated albumin for regional radiotherapy" @default.
• W2040994702 cites W100849715 @default.
• W2040994702 cites W136045749 @default.
• W2040994702 cites W1496482367 @default.
• W2040994702 cites W1557910602 @default.
• W2040994702 cites W1915280205 @default.
• W2040994702 cites W1969661948 @default.
• W2040994702 cites W2002820450 @default.
• W2040994702 cites W2004393008 @default.
• W2040994702 cites W2034616312 @default.
• W2040994702 cites W2038579311 @default.
• W2040994702 cites W2075947155 @default.
• W2040994702 cites W2085517936 @default.
• W2040994702 cites W2085950425 @default.
• W2040994702 cites W2105863383 @default.
• W2040994702 cites W2108070512 @default.
• W2040994702 cites W2125589864 @default.
• W2040994702 cites W2172041865 @default.
• W2040994702 cites W2185966235 @default.
• W2040994702 cites W222504707 @default.
• W2040994702 cites W2413095461 @default.
• W2040994702 cites W2419427567 @default.
• W2040994702 cites W2466247603 @default.
• W2040994702 doi "https://doi.org/10.1016/s0969-8051(97)80016-9" @default.
• W2040994702 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9290084" @default.
• W2040994702 hasPublicationYear "1997" @default.
• W2040994702 type Work @default.
• W2040994702 sameAs 2040994702 @default.
• W2040994702 citedByCount "3" @default.
• W2040994702 countsByYear W20409947022017 @default.
• W2040994702 crossrefType "journal-article" @default.
• W2040994702 hasAuthorship W2040994702A5009855950 @default.
• W2040994702 hasAuthorship W2040994702A5010422674 @default.
• W2040994702 hasAuthorship W2040994702A5012921572 @default.
• W2040994702 hasAuthorship W2040994702A5023225044 @default.
• W2040994702 hasAuthorship W2040994702A5026011582 @default.
• W2040994702 hasAuthorship W2040994702A5034452868 @default.
• W2040994702 hasAuthorship W2040994702A5044873442 @default.
• W2040994702 hasAuthorship W2040994702A5054069029 @default.
• W2040994702 hasAuthorship W2040994702A5083301071 @default.
• W2040994702 hasAuthorship W2040994702A5083595584 @default.
• W2040994702 hasConcept C104317684 @default.
• W2040994702 hasConcept C126322002 @default.
• W2040994702 hasConcept C177322064 @default.
• W2040994702 hasConcept C185592680 @default.
• W2040994702 hasConcept C202751555 @default.
• W2040994702 hasConcept C2777807558 @default.
• W2040994702 hasConcept C2778271344 @default.
• W2040994702 hasConcept C2778597219 @default.
• W2040994702 hasConcept C2780931953 @default.
• W2040994702 hasConcept C2989005 @default.
• W2040994702 hasConcept C43617362 @default.
• W2040994702 hasConcept C55493867 @default.
• W2040994702 hasConcept C71924100 @default.
• W2040994702 hasConceptScore W2040994702C104317684 @default.
• W2040994702 hasConceptScore W2040994702C126322002 @default.
• W2040994702 hasConceptScore W2040994702C177322064 @default.
• W2040994702 hasConceptScore W2040994702C185592680 @default.
• W2040994702 hasConceptScore W2040994702C202751555 @default.
• W2040994702 hasConceptScore W2040994702C2777807558 @default.
• W2040994702 hasConceptScore W2040994702C2778271344 @default.
• W2040994702 hasConceptScore W2040994702C2778597219 @default.
• W2040994702 hasConceptScore W2040994702C2780931953 @default.
• W2040994702 hasConceptScore W2040994702C2989005 @default.
• W2040994702 hasConceptScore W2040994702C43617362 @default.
• W2040994702 hasConceptScore W2040994702C55493867 @default.
• W2040994702 hasConceptScore W2040994702C71924100 @default.
• W2040994702 hasIssue "5" @default.
• W2040994702 hasLocation W20409947021 @default.
• W2040994702 hasLocation W20409947022 @default.
• W2040994702 hasOpenAccess W2040994702 @default.
• W2040994702 hasPrimaryLocation W20409947021 @default.
• W2040994702 hasRelatedWork W2002746760 @default.
• W2040994702 hasRelatedWork W2033790645 @default.
• W2040994702 hasRelatedWork W2040994702 @default.
• W2040994702 hasRelatedWork W2068410581 @default.
• W2040994702 hasRelatedWork W2127972294 @default.
• W2040994702 hasRelatedWork W2181515605 @default.
• W2040994702 hasRelatedWork W2296318195 @default.
• W2040994702 hasRelatedWork W2362918399 @default.
• W2040994702 hasRelatedWork W3173559534 @default.
• W2040994702 hasRelatedWork W2067014521 @default.
• W2040994702 hasVolume "24" @default.
• W2040994702 isParatext "false" @default.

• next