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- W2041004059 abstract "The function of the nuclear receptor (NR) in breast cancer progression has been investigated for decades. The majority of the nuclear receptors have well characterized natural ligands, but a few of them are orphan receptors for which no ligand has been identified. RORα, one member of the retinoid orphan nuclear receptor (ROR) subfamily of orphan receptors, regulates various cellular and pathological activities. RORα is commonly down-regulated and/or hypoactivated in breast cancer compared to normal mammary tissue. Expression of RORα suppresses malignant phenotypes in breast cancer cells, in vitro and in vivo. Activity of RORα can be categorized into the canonical and non-canonical nuclear receptor pathways, which in turn regulate various breast cancer cellular function, including cell proliferation, apoptosis and invasion. This information suggests that RORα is a potent tumor suppressor and a potential therapeutic target for breast cancer." @default.
- W2041004059 created "2016-06-24" @default.
- W2041004059 creator A5060015550 @default.
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- W2041004059 date "2012-11-26" @default.
- W2041004059 modified "2023-10-15" @default.
- W2041004059 title "RORα, a Potential Tumor Suppressor and Therapeutic Target of Breast Cancer" @default.
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- W2041004059 cites W1982575342 @default.
- W2041004059 cites W1986679879 @default.
- W2041004059 cites W1992638032 @default.
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- W2041004059 doi "https://doi.org/10.3390/ijms131215755" @default.
- W2041004059 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3546659" @default.
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