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- W2041018505 endingPage "482" @default.
- W2041018505 startingPage "462" @default.
- W2041018505 abstract "Phthalazinones are an important kind of nitrogen atom containing heterocyclic compounds due to their synthetic and pharmacological versatility. This fused heterocycle system represents a common structural feature for many bioactive compounds showing a variety of pharmacological activities such as anticancer, anti-diabetic, anti-asthmatic, antihistaminic, antihypertensive, antithrombotic, anti-inflammatory, analgesic, antidepressant or antimicrobial agents, which makes it an attractive scaffold for the design and development of new drugs. This review summarizes detailed and updated information, described in recent non-patent literature, about the most relevant pharmacological properties of phthalazinone derivatives, highlighting the application of this potent pharmacophore in drug discovery." @default.
- W2041018505 created "2016-06-24" @default.
- W2041018505 creator A5009684320 @default.
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- W2041018505 creator A5068996452 @default.
- W2041018505 creator A5069832986 @default.
- W2041018505 creator A5090598210 @default.
- W2041018505 date "2015-06-01" @default.
- W2041018505 modified "2023-10-10" @default.
- W2041018505 title "Phthalazin-1(2H)-one as a remarkable scaffold in drug discovery" @default.
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