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- W2041028680 endingPage "862" @default.
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- W2041028680 abstract "1. The adenosine triphosphate (ATP) binding cassette (ABC) transporters form one of the largest protein families encoded in the human genome, and more than 48 genes encoding human ABC transporters have been identified and sequenced. It has been reported that mutations of ABC protein genes are causative in several genetic disorders in humans. 2. Many human ABC transporters are involved in membrane transport of drugs, xenobiotics, endogenous substances or ions, thereby exhibiting a wide spectrum of biological functions. According to the new nomenclature of human ABC transporter genes, the 'ABCC' gene sub-family comprises three classes involving multidrug resistance-associated proteins (MRPs), sulfonylurea receptors (SURs), and a cystic fibrosis transmembrane conductance regulator (CFTR). 3. Molecular cloning studies have identified a total of ten members of the human MRP class including ABCC11, ABCC12, and ABCC13 (pseudo-gene) that have recently been characterized. 4. This review addresses the historical background and discovery of the ATP-driven xenobiotic export pumps (GS-X pumps) encoded by MRP genes, biological functions of ABC transporters belonging to the MRP class, and regulation of gene expression of MRPs by oxidative stress." @default.
- W2041028680 created "2016-06-24" @default.
- W2041028680 creator A5010418421 @default.
- W2041028680 creator A5011997875 @default.
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- W2041028680 creator A5050982797 @default.
- W2041028680 creator A5053987739 @default.
- W2041028680 creator A5079473036 @default.
- W2041028680 date "2008-08-01" @default.
- W2041028680 modified "2023-10-12" @default.
- W2041028680 title "MRP class of human ATP binding cassette (ABC) transporters: historical background and new research directions" @default.
- W2041028680 cites W1502426706 @default.
- W2041028680 cites W1504784308 @default.
- W2041028680 cites W1524216750 @default.
- W2041028680 cites W1552457962 @default.
- W2041028680 cites W1561096292 @default.
- W2041028680 cites W1562066535 @default.
- W2041028680 cites W1567645277 @default.
- W2041028680 cites W1570865673 @default.
- W2041028680 cites W1589987054 @default.
- W2041028680 cites W1597183523 @default.
- W2041028680 cites W1639721376 @default.
- W2041028680 cites W1646404713 @default.
- W2041028680 cites W1721237546 @default.
- W2041028680 cites W1888874925 @default.
- W2041028680 cites W1890023926 @default.
- W2041028680 cites W1896547048 @default.
- W2041028680 cites W1965410481 @default.
- W2041028680 cites W1966167155 @default.
- W2041028680 cites W1966431705 @default.
- W2041028680 cites W1967558645 @default.
- W2041028680 cites W1970031380 @default.
- W2041028680 cites W1970218983 @default.
- W2041028680 cites W1971465028 @default.
- W2041028680 cites W1973141016 @default.
- W2041028680 cites W1974338599 @default.
- W2041028680 cites W1975482089 @default.
- W2041028680 cites W1976270928 @default.
- W2041028680 cites W1977754424 @default.
- W2041028680 cites W1980679007 @default.
- W2041028680 cites W1983178225 @default.
- W2041028680 cites W1983232483 @default.
- W2041028680 cites W1983548371 @default.
- W2041028680 cites W1985998919 @default.
- W2041028680 cites W1990547924 @default.
- W2041028680 cites W1997929265 @default.
- W2041028680 cites W2001838995 @default.
- W2041028680 cites W2003962390 @default.
- W2041028680 cites W2005064657 @default.
- W2041028680 cites W2005160619 @default.
- W2041028680 cites W2005604459 @default.
- W2041028680 cites W2006514357 @default.
- W2041028680 cites W2008344420 @default.
- W2041028680 cites W2009593801 @default.
- W2041028680 cites W2009874447 @default.
- W2041028680 cites W2011303937 @default.
- W2041028680 cites W2012935034 @default.
- W2041028680 cites W2013485244 @default.
- W2041028680 cites W2014424798 @default.
- W2041028680 cites W2018398124 @default.
- W2041028680 cites W2026383454 @default.
- W2041028680 cites W2027380419 @default.
- W2041028680 cites W2030234071 @default.
- W2041028680 cites W2030763326 @default.
- W2041028680 cites W2033652401 @default.
- W2041028680 cites W2033802853 @default.
- W2041028680 cites W2034018713 @default.
- W2041028680 cites W2035122341 @default.
- W2041028680 cites W2035773315 @default.
- W2041028680 cites W2037015095 @default.
- W2041028680 cites W2037103758 @default.
- W2041028680 cites W2038600597 @default.
- W2041028680 cites W2039384470 @default.
- W2041028680 cites W2040315766 @default.
- W2041028680 cites W2041641047 @default.
- W2041028680 cites W2042674837 @default.
- W2041028680 cites W2043817490 @default.
- W2041028680 cites W2045095333 @default.
- W2041028680 cites W2046460191 @default.
- W2041028680 cites W2048425013 @default.
- W2041028680 cites W2050994990 @default.
- W2041028680 cites W2051946794 @default.
- W2041028680 cites W2052413452 @default.
- W2041028680 cites W2052548231 @default.
- W2041028680 cites W2053350368 @default.
- W2041028680 cites W2053671318 @default.
- W2041028680 cites W2053706150 @default.
- W2041028680 cites W2054131280 @default.
- W2041028680 cites W2055335590 @default.
- W2041028680 cites W2055706314 @default.
- W2041028680 cites W2055988844 @default.
- W2041028680 cites W2057271651 @default.
- W2041028680 cites W2057407100 @default.
- W2041028680 cites W2060297699 @default.
- W2041028680 cites W2060367291 @default.
- W2041028680 cites W2068779347 @default.
- W2041028680 cites W2070972281 @default.
- W2041028680 cites W2071756286 @default.