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- W2041032992 abstract "We have characterized at the molecular level several polar mutations in four different cistrons of the his operon of S. typhimurium. An analysis of the his-specific transcripts produced in vivo In the mutant strains, together with in vitro transcription assays, led to the identification of several cryptic Rho-dependent transcription termination elements within the his operon that are activated by the uncoupling of transcription and translation. Common features of these elements were sought and found with a computer program. We have identified a consensus motif, consisting of a cytosine-rich and guanosine-poor region, that is located upstream of the heterogeneous 3′ endpoints of the prematurely terminated in vivo transcripts and that is present in all the Rho-dependent transcription terminators described thus far." @default.
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- W2041032992 date "1991-02-01" @default.
- W2041032992 modified "2023-10-13" @default.
- W2041032992 title "A consensus motif common to all rho-dependent prokaryotic transcription terminators" @default.
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- W2041032992 doi "https://doi.org/10.1016/0092-8674(91)90239-u" @default.
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