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- W2041036301 abstract "Seventeen patients treated with procainamide for cardiac ventricular arrhythmias were followed for up to 40 weeks. Immunological data as a clue to developing the systemic lupus erythematosus (SLE)-like syndrome was emphasized. Ten patients developed antinuclear antibodies (IgG or IgM), but no increase in the plasma concentration of the complement split product C3d or immune complexes, measured by two different methods, was demonstrated. This finding is in contrast to the high levels of both C3d and immune complexes in SLE. The discrepancy may be caused by a lack of immune complex mediated complement activation by the procainamide induced antibodies, or may be due to a difference in severity of disease. The acetylator phenotype of the patients was determined but due to the low frequency of fast acetylators no comparison of the immunological response of the two phenotypes could be done." @default.
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- W2041036301 date "2009-04-24" @default.
- W2041036301 modified "2023-09-25" @default.
- W2041036301 title "Plasma Concentrations of Complement Split Product C3d and Immune Complexes after Procainamide Induced Production of Antinuclear Antibodies" @default.
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- W2041036301 doi "https://doi.org/10.1111/j.0954-6820.1986.tb02792.x" @default.
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