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- W2041102005 abstract "Abstract Background Perioral dermatitis (POD) is a common skin disease and difficult to treat. Pimecrolimus cream (1%) successfully controls atopic eczema. Objective Our aim was to investigate its efficacy in POD. Study design Single‐centre, randomized, double‐blind, vehicle‐controlled study including 40 POD patients with a 4‐week treatment and a 4‐week follow‐up. Efficacy was assessed by a novel Perioral Dermatitis Severity Index (PODSI) and Finlay's Dermatology Life Quality Index (DLQI). Setting Outpatient clinics of a large dermatological hospital in Munich, Germany. Results During treatment, the PODSI was significantly lower in the pimecrolimus group compared with vehicle ( P = 0.005–0.02) whereas at follow‐up, no significant differences were observed. At week 2, the responder rates (≥ 50% PODSI improvement) were 50% with pimecrolimus cream (1%) and 25% with vehicle ( P = 0.095). DLQI was improved in pimecrolimus group compared with vehicle. Conclusion Results suggest that pimecrolimus cream (1%) effectively treats acute‐stage POD." @default.
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- W2041102005 date "2007-09-14" @default.
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- W2041102005 title "Pimecrolimus cream (1%) efficacy in perioral dermatitis ? results of a randomized, double-blind, vehicle-controlled study in 40 patients" @default.
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- W2041102005 doi "https://doi.org/10.1111/j.1468-3083.2007.02191.x" @default.
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