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• W2041128343 abstract "Serum lipoproteins, separated by preparative ultracentrifugation and the activity of the plasma enzyme lecithin : cholesterol acyltransferase (LCAT) have been measured in insulin-dependent diabetics, non-insulin-dependent diabetics and in age-matched non-diabetic controls. In the insulin-dependent diabetics, mean total serum cholesterol and high density lipoprotein cholesterol (HDL-C) concentrations were significantly higher than in controls. Non-insulin-dependent diabetics had significantly raised total triglycerides and cholesterol, but HDL-C levels were essentially normal. The increased low density lipoprotein cholesterol (LDL-C) in both diabetic groups was statistically significant in men. A methodological study of HDL separation techniques was carried out to facilitate interpretation of these findings. Mean LCAT activity, by a method reflecting combined enzyme and substrate effects, was significantly increased in these diabetic groups. The results confirm recent reports of a raised HDL-C in those insulin-dependent diabetics who are prone to coronary heart disease." @default.
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• W2041128343 date "1979-12-01" @default.
• W2041128343 modified "2023-10-17" @default.
• W2041128343 title "Lipoproteins and plasma cholesterol esterification in normal and diabetic subjects" @default.
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• W2041128343 doi "https://doi.org/10.1016/0021-9150(79)90068-6" @default.
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