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- W2041134517 abstract "We describe the synthesis of the dip (di-picolyl-carboxylate) bifunctional chelator system, capable of fast coordination of Cu2+, 64Cu2+ and Co2+, as well as the [M(CO)3]+-core (M = 99mTc, Re); it displays a variety of binding modes—tridentate when protected, tetradentate when deprotected. Syntheses of both the benzyl-nitro derivative and the benzyl-amino derivatives are described. The latter was coupled to biotin to show the viability of the system for functionalization with biomolecules. Besides coordination chemistry with stable isotopes, we also present labelling data with 64Cu and 99mTc, as well as in vitro stability studies." @default.
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- W2041134517 date "2011-01-01" @default.
- W2041134517 modified "2023-09-25" @default.
- W2041134517 title "One to chelate them all: investigation of a versatile, bifunctional chelator for 64Cu, 99mTc, Re and Co" @default.
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- W2041134517 doi "https://doi.org/10.1039/c0dt01458c" @default.
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