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- W2041168086 abstract "La cocaína es una de las drogas más consumidas en el mundo. Ejerce sus efectos mediante el bloqueo de los transportadores de monoaminas, como la dopamina y la noradrenalina. En la presente revisión se describen algunos de los cambios más relevantes que se producen en el cerebro como consecuencia de la inhibición de estos transportadores, como son las alteraciones en las vías de recompensa, la citoarquitectura cortical, las trofinas cerebrales y la barrera hematoencefálica, y cómo estos cambios se asocian a los procesos de adicción y al daño neuronal inducidos por el consumo de cocaína. Cocaine is one of the most widely extended drugs of abuse. It acts by blocking the monoamines transporters in the synaptic membrane. This review describes some of the most relevant cocaine-induced brain alterations in reward pathways, cortical cytoarchitecture, brain trofic factors or blood brain barrier and how these alterations may be involved in cocaine-induced addictive processes and brain injury." @default.
- W2041168086 created "2016-06-24" @default.
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- W2041168086 date "2010-10-01" @default.
- W2041168086 modified "2023-10-16" @default.
- W2041168086 title "Cocaína y cerebro" @default.
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- W2041168086 doi "https://doi.org/10.1016/s1575-0973(10)70025-8" @default.
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