FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041274811> ?p ?o ?g. }

• W2041274811 endingPage "A60" @default.
• W2041274811 startingPage "A59" @default.
• W2041274811 abstract "<h3>Objective</h3> To examine the association of circulating levels of 25-hydroxyvitamin D (25(OH)D) and ionised calcium with lung function and sensitisation to common environmental allergens in adolescents (12–19 years) and adults (20–59 years). <h3>Design</h3> Cross-sectional study. <h3>Participants</h3> Participants of the US third National Health and Nutrition Examination Survey <b>(</b>NHANES III), a representative sample of the non-institutionalised US population, with data on serum 25(OH)D levels and spirometry (adolescents, n=2074; adults, n=4647) and 25(OH)D levels and skin prick tests (adolescents, n=1914; adults, n=4782). <h3>Main Outcome Measure</h3> Forced expiratory volume in 1 s (FEV₁) and forced vital capacity (FVC) from Spirometry. Skin prick test responses to a standardised allergen panel comprising indoor allergens (house mite; <i>Dermatophagoides farinae</i>, cat, German cockroach), outdoor allergens (short ragweed, perennial rye, <i>Alternaria alternata</i>, Bermuda grass, Russian thistle and white oak), and a food allergen (peanut) and a negative control. Positive allergen response was defined as maximal weal diameter ≥3 mm for allergen and <3 mm for negative control. <h3>Results</h3> Serum levels of 25(OH)D were positively associated with FVC in adolescents (0.073 (0.025–0.121) SD) and adults (0.045 (0.013–0.078) SD) and with FEV₁ in adults (0.050 (0.013–0.087)) after adjusting for health status, previously diagnosed respiratory/allergic diseases, supplement use, household pets and demographic and socioeconomic characteristics. These associations were independent of circulating calcium levels. Calcium levels were not associated with lung function in either age group. In adults, modest positive associations of ionised calcium with sensitisation to allergens of grass origin were observed (OR per SD, 1.12(1.00–1.26) for white oak and 1.13(1.01–1.26) for Bermuda grass in fully adjusted model). These associations were independent of 25(OH)D levels. All associations remained after further adjustment for smoking and alcohol use. <h3>Conclusion</h3> We found a cross-sectional association between serum 25(OH)D levels and lung function, which does not appear to be driven by increased allergen sensitisation. By contrast we report a novel positive association between serum levels of ionised calcium and grass allergen sensitisation in adults, which is independent of vitamin D." @default.
• W2041274811 created "2016-06-24" @default.
• W2041274811 creator A5002738902 @default.
• W2041274811 creator A5016704551 @default.
• W2041274811 creator A5079698453 @default.
• W2041274811 creator A5082012307 @default.
• W2041274811 date "2010-09-01" @default.
• W2041274811 modified "2023-09-27" @default.
• W2041274811 title "P67 The associations of serum 25-hydroxy-vitamin D and ionised calcium with lung function and allergen skin prick tests in adolescents and adults: findings from a cross-sectional study using the US Third National Health and Nutrition Examination Survey (NHANES III)" @default.
• W2041274811 doi "https://doi.org/10.1136/jech.2010.120477.67" @default.
• W2041274811 hasPublicationYear "2010" @default.
• W2041274811 type Work @default.
• W2041274811 sameAs 2041274811 @default.
• W2041274811 citedByCount "0" @default.
• W2041274811 crossrefType "journal-article" @default.
• W2041274811 hasAuthorship W2041274811A5002738902 @default.
• W2041274811 hasAuthorship W2041274811A5016704551 @default.
• W2041274811 hasAuthorship W2041274811A5079698453 @default.
• W2041274811 hasAuthorship W2041274811A5082012307 @default.
• W2041274811 hasBestOaLocation W20412748111 @default.
• W2041274811 hasConcept C124490489 @default.
• W2041274811 hasConcept C126322002 @default.
• W2041274811 hasConcept C142052008 @default.
• W2041274811 hasConcept C142724271 @default.
• W2041274811 hasConcept C165637977 @default.
• W2041274811 hasConcept C203014093 @default.
• W2041274811 hasConcept C207480886 @default.
• W2041274811 hasConcept C2776042228 @default.
• W2041274811 hasConcept C2777714996 @default.
• W2041274811 hasConcept C2779740938 @default.
• W2041274811 hasConcept C2779874844 @default.
• W2041274811 hasConcept C2780333948 @default.
• W2041274811 hasConcept C2780510475 @default.
• W2041274811 hasConcept C2780931586 @default.
• W2041274811 hasConcept C2908647359 @default.
• W2041274811 hasConcept C3018587741 @default.
• W2041274811 hasConcept C55520419 @default.
• W2041274811 hasConcept C71924100 @default.
• W2041274811 hasConcept C75603125 @default.
• W2041274811 hasConcept C99454951 @default.
• W2041274811 hasConceptScore W2041274811C124490489 @default.
• W2041274811 hasConceptScore W2041274811C126322002 @default.
• W2041274811 hasConceptScore W2041274811C142052008 @default.
• W2041274811 hasConceptScore W2041274811C142724271 @default.
• W2041274811 hasConceptScore W2041274811C165637977 @default.
• W2041274811 hasConceptScore W2041274811C203014093 @default.
• W2041274811 hasConceptScore W2041274811C207480886 @default.
• W2041274811 hasConceptScore W2041274811C2776042228 @default.
• W2041274811 hasConceptScore W2041274811C2777714996 @default.
• W2041274811 hasConceptScore W2041274811C2779740938 @default.
• W2041274811 hasConceptScore W2041274811C2779874844 @default.
• W2041274811 hasConceptScore W2041274811C2780333948 @default.
• W2041274811 hasConceptScore W2041274811C2780510475 @default.
• W2041274811 hasConceptScore W2041274811C2780931586 @default.
• W2041274811 hasConceptScore W2041274811C2908647359 @default.
• W2041274811 hasConceptScore W2041274811C3018587741 @default.
• W2041274811 hasConceptScore W2041274811C55520419 @default.
• W2041274811 hasConceptScore W2041274811C71924100 @default.
• W2041274811 hasConceptScore W2041274811C75603125 @default.
• W2041274811 hasConceptScore W2041274811C99454951 @default.
• W2041274811 hasIssue "Suppl 1" @default.
• W2041274811 hasLocation W20412748111 @default.
• W2041274811 hasOpenAccess W2041274811 @default.
• W2041274811 hasPrimaryLocation W20412748111 @default.
• W2041274811 hasRelatedWork W153523923 @default.
• W2041274811 hasRelatedWork W2019808322 @default.
• W2041274811 hasRelatedWork W2067251704 @default.
• W2041274811 hasRelatedWork W2082677861 @default.
• W2041274811 hasRelatedWork W2375063122 @default.
• W2041274811 hasRelatedWork W2804634747 @default.
• W2041274811 hasRelatedWork W2987543560 @default.
• W2041274811 hasRelatedWork W4206796918 @default.
• W2041274811 hasRelatedWork W4283808193 @default.
• W2041274811 hasRelatedWork W2187449354 @default.
• W2041274811 hasVolume "64" @default.
• W2041274811 isParatext "false" @default.
• W2041274811 isRetracted "false" @default.
• W2041274811 magId "2041274811" @default.
• W2041274811 workType "article" @default.