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- W2041331050 abstract "Tramér MR, Carroll D, Campbell FA , et al. Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review. BMJ2001 Jul 7; 323 : 16 –21 . [OpenUrl][1][Abstract/FREE Full Text][2] QUESTION: In patients with chemotherapy-induced sickness, what are the antiemetic efficacy and adverse effects of cannabinoids? Full publications of studies were identified by searching Medline (from 1966), EMBASE/Excerpta Medica (from 1982), and the Cochrane Library (2000, Issue 3) with the terms cannabinoids, cannabis, nabilone, tetrahydrocannabinol (THC), THC, marihuana, marijuana, levonantradol, dronabinol, randomized, and human. Bibliographies of relevant studies were checked. Studies were selected if they were randomised controlled trials (RCTs) comparing the antiemetic efficacy of cannabis with any other antiemetic agent or placebo in patients having chemotherapy. Data were extracted on study quality, patients, interventions and regimens, and outcomes. 30 RCTs (1366 patients) published between 1975 and 1997 met the selection criteria. The mean number of patients per study was 46 (range 8 to 139 patients). 16 studies examined oral nabilone, 13 examined oral dronabinol, and 1 examined intramuscular levonantradol. The active control groups were administered prochlorperazine (12 studies), metoclopramide (4 studies), chlorpromazine (2 studies), thiethylperazine (1 study), … [1]: {openurl}?query=rft.jtitle%253DBMJ%26rft.stitle%253DBMJ%26rft.issn%253D0007-1447%26rft.aulast%253DTramer%26rft.auinit1%253DM.%2BR%26rft.volume%253D323%26rft.issue%253D7303%26rft.spage%253D16%26rft.epage%253D16%26rft.atitle%253DCannabinoids%2Bfor%2Bcontrol%2Bof%2Bchemotherapy%2Binduced%2Bnausea%2Band%2Bvomiting%253A%2Bquantitative%2Bsystematic%2Breview%26rft_id%253Dinfo%253Adoi%252F10.1136%252Fbmj.323.7303.16%26rft_id%253Dinfo%253Apmid%252F11440936%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bmj&resid=323/7303/16&atom=%2Febmed%2F7%2F1%2F25.atom" @default.
- W2041331050 created "2016-06-24" @default.
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- W2041331050 date "2002-01-01" @default.
- W2041331050 modified "2023-09-27" @default.
- W2041331050 title "Review: cannabinoids control chemotherapy-induced nausea and vomiting but increase the risk of side effects" @default.
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- W2041331050 doi "https://doi.org/10.1136/ebm.7.1.25" @default.
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