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- W2041380889 abstract "In our efforts to find new whitening agent from natural resources, we focused on wood of Artocarpus heterophyllus which shows anti-melanogenesis activity. By activity-guided fractionation of A. heterophyllus wood extract, a new prenylated flavonoid, 3-prenyl luteolin (1) was isolated. The IC50 of mushroom tyrosinase inhibitotry activity of 1 was 76.3 µM. The results of the comparison with that of luteolin showed the prenyl substituent at C-3 position of 1 play an important role for revealing tyrosinase inhibition. In melanin formation inhibition on B16 melanoma cells, IC50 of 1 was 56.7 µM with less cytotoxicity." @default.
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- W2041380889 date "2010-09-01" @default.
- W2041380889 modified "2023-10-13" @default.
- W2041380889 title "3-Prenyl luteolin, a new prenylated flavone with melanin biosynthesis inhibitory activity from wood of Artocarpus heterophyllus" @default.
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- W2041380889 doi "https://doi.org/10.1016/j.fitote.2010.03.011" @default.
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