FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2041420525> ?p ?o ?g. }

• W2041420525 endingPage "1445" @default.
• W2041420525 startingPage "1441" @default.
• W2041420525 abstract "Despite the prominent peak of N-acetylaspartate (NAA) in proton MR spectroscopy ((1)H-MR spectroscopy) of the adult brain and its almost exclusive presence in neuronal cells, the total amount of NAA, regarded as their marker, is difficult to obtain due to signal contamination from the skull lipids. This article compares the performance of 2 methods that overcome this difficulty to yield the whole-brain NAA signal, important for the assessment of the total disease load in diffuse neurologic disorders.The heads of 12 healthy volunteers, 3 women and 9 men, 31.0 +/- 7.1 years of age, were scanned at 3T by using 2 nonlocalizing (1)H-MR spectroscopy sequences: One nulls the NAA (TI = 940 ms) every second acquisition by inversion-recovery to cancel the signals of the lipids (T1 << TI) in an add-subtract scheme. The other nulls the signal of the lipids (TI = 155 ms) directly after each acquisition, requiring half as many averages for the same signal-to-noise ratio. Each sequence was repeated 3 times back-to-back on 3 occasions, and the comparison criteria were intrasubject precision (reproducibility) and total measurement duration.NAA nulling is nearly twice as precise in its intrinsic back-to-back (5.8% versus 8.6%) as well as longitudinal (10.6% versus 19.7%) coefficients of variation compared with lipid nulling, but at the cost of double the acquisition time.When speed is a more stringent requirement than precision, the new lipid-nulling sequence is a viable alternative. For precision in cross-sectional or longitudinal global NAA quantification, however, NAA nulling is still the approach of choice despite its x2 ( approximately 5 minutes) time penalty compared with the lipid-nulling approach." @default.
• W2041420525 created "2016-06-24" @default.
• W2041420525 creator A5020136275 @default.
• W2041420525 creator A5045154561 @default.
• W2041420525 creator A5045539537 @default.
• W2041420525 creator A5051811962 @default.
• W2041420525 creator A5052171046 @default.
• W2041420525 creator A5054828860 @default.
• W2041420525 creator A5067481396 @default.
• W2041420525 creator A5078026212 @default.
• W2041420525 creator A5080608443 @default.
• W2041420525 date "2008-06-12" @default.
• W2041420525 modified "2023-10-08" @default.
• W2041420525 title "Whole-Brain<i>N</i>-Acetylaspartate MR Spectroscopic Quantification: Performance Comparison of Metabolite versus Lipid Nulling" @default.
• W2041420525 cites W1583604396 @default.
• W2041420525 cites W1966788881 @default.
• W2041420525 cites W1991796448 @default.
• W2041420525 cites W2013522256 @default.
• W2041420525 cites W2023630108 @default.
• W2041420525 cites W2030471614 @default.
• W2041420525 cites W2035586509 @default.
• W2041420525 cites W2045290032 @default.
• W2041420525 cites W2050557825 @default.
• W2041420525 cites W2051571725 @default.
• W2041420525 cites W2052065888 @default.
• W2041420525 cites W2068465493 @default.
• W2041420525 cites W2083898925 @default.
• W2041420525 cites W2090709719 @default.
• W2041420525 cites W2094454256 @default.
• W2041420525 cites W2096438243 @default.
• W2041420525 cites W2102118295 @default.
• W2041420525 cites W2121063409 @default.
• W2041420525 cites W2126125655 @default.
• W2041420525 cites W2137989709 @default.
• W2041420525 cites W2144867092 @default.
• W2041420525 cites W2158388157 @default.
• W2041420525 cites W2158514967 @default.
• W2041420525 cites W2740095624 @default.
• W2041420525 cites W4230713808 @default.
• W2041420525 doi "https://doi.org/10.3174/ajnr.a1171" @default.
• W2041420525 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2576739" @default.
• W2041420525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18556356" @default.
• W2041420525 hasPublicationYear "2008" @default.
• W2041420525 type Work @default.
• W2041420525 sameAs 2041420525 @default.
• W2041420525 citedByCount "10" @default.
• W2041420525 countsByYear W20414205252012 @default.
• W2041420525 countsByYear W20414205252014 @default.
• W2041420525 countsByYear W20414205252017 @default.
• W2041420525 countsByYear W20414205252018 @default.
• W2041420525 countsByYear W20414205252020 @default.
• W2041420525 countsByYear W20414205252021 @default.
• W2041420525 countsByYear W20414205252022 @default.
• W2041420525 countsByYear W20414205252023 @default.
• W2041420525 crossrefType "journal-article" @default.
• W2041420525 hasAuthorship W2041420525A5020136275 @default.
• W2041420525 hasAuthorship W2041420525A5045154561 @default.
• W2041420525 hasAuthorship W2041420525A5045539537 @default.
• W2041420525 hasAuthorship W2041420525A5051811962 @default.
• W2041420525 hasAuthorship W2041420525A5052171046 @default.
• W2041420525 hasAuthorship W2041420525A5054828860 @default.
• W2041420525 hasAuthorship W2041420525A5067481396 @default.
• W2041420525 hasAuthorship W2041420525A5078026212 @default.
• W2041420525 hasAuthorship W2041420525A5080608443 @default.
• W2041420525 hasBestOaLocation W20414205251 @default.
• W2041420525 hasConcept C103191249 @default.
• W2041420525 hasConcept C121332964 @default.
• W2041420525 hasConcept C126322002 @default.
• W2041420525 hasConcept C126838900 @default.
• W2041420525 hasConcept C131021393 @default.
• W2041420525 hasConcept C13412647 @default.
• W2041420525 hasConcept C143409427 @default.
• W2041420525 hasConcept C185592680 @default.
• W2041420525 hasConcept C199360897 @default.
• W2041420525 hasConcept C2777477808 @default.
• W2041420525 hasConcept C2779843651 @default.
• W2041420525 hasConcept C2989005 @default.
• W2041420525 hasConcept C32891209 @default.
• W2041420525 hasConcept C41008148 @default.
• W2041420525 hasConcept C43617362 @default.
• W2041420525 hasConcept C46141821 @default.
• W2041420525 hasConcept C62520636 @default.
• W2041420525 hasConcept C71924100 @default.
• W2041420525 hasConcept C761482 @default.
• W2041420525 hasConcept C76155785 @default.
• W2041420525 hasConcept C97855336 @default.
• W2041420525 hasConcept C9893847 @default.
• W2041420525 hasConceptScore W2041420525C103191249 @default.
• W2041420525 hasConceptScore W2041420525C121332964 @default.
• W2041420525 hasConceptScore W2041420525C126322002 @default.
• W2041420525 hasConceptScore W2041420525C126838900 @default.
• W2041420525 hasConceptScore W2041420525C131021393 @default.
• W2041420525 hasConceptScore W2041420525C13412647 @default.
• W2041420525 hasConceptScore W2041420525C143409427 @default.
• W2041420525 hasConceptScore W2041420525C185592680 @default.
• W2041420525 hasConceptScore W2041420525C199360897 @default.
• W2041420525 hasConceptScore W2041420525C2777477808 @default.
• W2041420525 hasConceptScore W2041420525C2779843651 @default.

• next