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- W2041481102 abstract "This paper describes the ultrastructure of the adrenal cortex in two children with Cushing's disease. The main ultrastructural changes were observed in the zonae fasciculata and reticularis. The hyperplastic cells seen by light microscopy in diffuse hyperplasia of the adrenal cortex of Cushing's disease appeared as electron light cells at the ultrastructural level. Their appearance resulted from dilatation and hyperplasia of the smooth-surfaced endoplasmic reticulum and a decrease in the size of lipid globules. Mitochondrial changes included two types of mitochondria, increased electron density of the matrix, outpouching of the outer membrane, intramitochondrial dense bodies, and tubular cristae. Our observations tend to agree with the findings of others in experimental animals and to differ with a previous report on Cushing's disease." @default.
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- W2041481102 date "1970-12-01" @default.
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- W2041481102 title "Ultrastructure of the adrenal cortex in Cushing's disease in children" @default.
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- W2041481102 doi "https://doi.org/10.1016/s0046-8177(70)80059-4" @default.
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