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- W2041491363 abstract "In plant roots, patterning of two types of water-conducting xylem tissue is determined by a signalling system that involves the reciprocal dance of a mobile transcription factor and mobile microRNAs. A study of plant root development in the classic plant model Arabidopsis implicates a microRNA, miRNA165/6, in communication between cells and as a determinant of root cell fate. Patterning of the xylem tubes that transport water and solutes from root to shoot is shown to depend on a novel bi-directional signalling pathway involving cell-to-cell movement of a transcription factor in one direction, and microRNAs in the other. The transcription factor, SHORT ROOT, produced in the vascular cylinder, moves into the endodermis where, with SCARECROW, it activates the microRNAs MIR165a and MIR166b, which then, back in the vascular cells, degrade their target messenger RNAs encoding class III homeodomain-leucine zipper transcription factors. The involvement of a cascade of evolutionarily conserved transcription factors and miRNAs in this regulatory pathway suggests that it may be an evolutionary adaptation to terrestrial growth." @default.
- W2041491363 created "2016-06-24" @default.
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- W2041491363 date "2010-05-01" @default.
- W2041491363 modified "2023-09-30" @default.
- W2041491363 title "Roots respond to an inner calling" @default.
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- W2041491363 doi "https://doi.org/10.1038/465299a" @default.
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